ENSG00000170122


Homo sapiens

Features
Gene ID: ENSG00000170122
  
Biological name :FOXD4
  
Synonyms : forkhead box D4 / FOXD4 / Q12950
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: p24.3
Gene start: 116231
Gene end: 118204
  
Corresponding Affymetrix probe sets: 217032_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000371940
NCBI entrez gene - 2298     See in Manteia.
OMIM - 601092
RefSeq - NM_207305
RefSeq Peptide - NP_997188
swissprot - Q12950
Ensembl - ENSG00000170122
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 foxd3ENSDARG00000021032Danio rerio
 Foxd4ENSMUSG00000051490Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q3SYB3 / FOXD4L6 / forkhead box D4 like 6ENSG0000027351481
Q6VB84 / FOXD4L3 / forkhead box D4 like 3ENSG0000018755981
Q5VV16 / FOXD4L5 / forkhead box D4 like 5ENSG0000020477980
Q8WXT5 / FOXD4L4 / forkhead box D4 like 4ENSG0000018465980
Q9NU39 / FOXD4L1 / forkhead box D4 like 1ENSG0000018449269
FOXD2 / O60548 / forkhead box D2ENSG0000018656433
FOXD3 / Q9UJU5 / forkhead box D3ENSG0000018714032
FOXD1 / Q16676 / forkhead box D1ENSG0000025149331
FOXE1 / O00358 / forkhead box E1ENSG0000017891925
FOXE3 / Q13461 / forkhead box E3ENSG0000018679025
FOXG1 / P55316 / forkhead box G1ENSG0000017616522
FOXF2 / Q12947 / forkhead box F2ENSG0000013727322
FOXF1 / Q12946 / forkhead box F1ENSG0000010324121
FOXQ1 / Q9C009 / forkhead box Q1ENSG0000016437921
AC187653.1ENSG0000024876720
FOXP4 / Q8IVH2 / forkhead box P4ENSG0000013716614
FOXP2 / O15409 / forkhead box P2ENSG0000012857314
FOXH1 / O75593 / forkhead box H1ENSG0000016097314
FOXP1 / Q9H334 / forkhead box P1ENSG0000011486113
FOXP3 / Q9BZS1 / forkhead box P3ENSG0000004976810


Protein motifs (from Interpro)
Interpro ID Name
 IPR001766  Fork head domain
 IPR030456  Fork head domain conserved site 2
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0009653 anatomical structure morphogenesis IBA
 biological_processGO:0030154 cell differentiation IBA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0008301 DNA binding, bending ISS
 molecular_functionGO:0043565 sequence-specific DNA binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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