ENSG00000186564


Homo sapiens

Features
Gene ID: ENSG00000186564
  
Biological name :FOXD2
  
Synonyms : forkhead box D2 / FOXD2 / O60548
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p33
Gene start: 47436017
Gene end: 47440691
  
Corresponding Affymetrix probe sets: 207653_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000335493
NCBI entrez gene - 2306     See in Manteia.
OMIM - 602211
RefSeq - NM_004474
RefSeq Peptide - NP_004465
swissprot - O60548
Ensembl - ENSG00000186564
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 foxd1ENSDARG00000029179Danio rerio
 foxd2ENSDARG00000058133Danio rerio
 foxd5ENSDARG00000042485Danio rerio
 zgc:162612ENSDARG00000079699Danio rerio
 Foxd2ENSMUSG00000055210Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FOXD1 / Q16676 / forkhead box D1ENSG0000025149342
FOXD3 / Q9UJU5 / forkhead box D3ENSG0000018714036
Q9NU39 / FOXD4L1 / forkhead box D4 like 1ENSG0000018449232
FOXD4 / Q12950 / forkhead box D4ENSG0000017012230
Q5VV16 / FOXD4L5 / forkhead box D4 like 5ENSG0000020477929
Q8WXT5 / FOXD4L4 / forkhead box D4 like 4ENSG0000018465929
Q3SYB3 / FOXD4L6 / forkhead box D4 like 6ENSG0000027351429
Q6VB84 / FOXD4L3 / forkhead box D4 like 3ENSG0000018755929
FOXE1 / O00358 / forkhead box E1ENSG0000017891924
FOXE3 / Q13461 / forkhead box E3ENSG0000018679023
FOXG1 / P55316 / forkhead box G1ENSG0000017616523
FOXQ1 / Q9C009 / forkhead box Q1ENSG0000016437923
FOXF2 / Q12947 / forkhead box F2ENSG0000013727321
FOXF1 / Q12946 / forkhead box F1ENSG0000010324119
AC187653.1ENSG0000024876719
FOXP4 / Q8IVH2 / forkhead box P4ENSG0000013716616
FOXH1 / O75593 / forkhead box H1ENSG0000016097316
FOXP2 / O15409 / forkhead box P2ENSG0000012857315
FOXP1 / Q9H334 / forkhead box P1ENSG0000011486114
FOXP3 / Q9BZS1 / forkhead box P3ENSG0000004976810


Protein motifs (from Interpro)
Interpro ID Name
 IPR001766  Fork head domain
 IPR018122  Fork head domain conserved site1
 IPR030456  Fork head domain conserved site 2
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0009653 anatomical structure morphogenesis IBA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IC
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0043565 sequence-specific DNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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