ENSMUSG00000055210


Mus musculus

Features
Gene ID: ENSMUSG00000055210
  
Biological name :Foxd2
  
Synonyms : Forkhead box protein D2 / Foxd2 / O35392
  
Possible biological names infered from orthology : forkhead box D2 / O60548
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: D1
Gene start: 114906282
Gene end: 114908873
  
Corresponding Affymetrix probe sets: 10515159 (MoGene1.0st)   1442315_at (Mouse Genome 430 2.0 Array)   1450289_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000066868
NCBI entrez gene - 17301     See in Manteia.
MGI - MGI:1347471
RefSeq - NM_008593
RefSeq Peptide - NP_032619
swissprot - O35392
Ensembl - ENSMUSG00000055210
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 foxd1ENSDARG00000029179Danio rerio
 foxd2ENSDARG00000058133Danio rerio
 foxd5ENSDARG00000042485Danio rerio
 zgc:162612ENSDARG00000079699Danio rerio
 FOXD2ENSG00000186564Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Foxd1 / Q61345 / Forkhead box protein D1 / Q16676* / forkhead box D1*ENSMUSG0000007830241
Foxd3 / forkhead box D3 / Q9UJU5*ENSMUSG0000006726135
Foxd4 / Q60688 / Forkhead box protein D4 / Q9NU39* / Q12950* / Q3SYB3* / Q5VV16* / Q6VB84* / Q8WXT5* / FOXD4L3* / FOXD4L4* / FOXD4L5* / FOXD4L6* / FOXD4L1* / forkhead box D4* / forkhead bo...ENSMUSG0000005149029
Foxe1 / Q8R2I0 / Forkhead box protein E1 / O00358* / forkhead box E1*ENSMUSG0000007099025
Foxg1 / Q60987 / Forkhead box protein G1 / P55316* / forkhead box G1*ENSMUSG0000002095024
Foxf2 / O54743 / Forkhead box protein F2 / Q12947* / forkhead box F2*ENSMUSG0000003840223
Foxe3 / Q9QY14 / Forkhead box protein E3 / Q13461* / forkhead box E3*ENSMUSG0000004451822
Foxq1 / O70220 / Forkhead box protein Q1 / Q9C009* / forkhead box Q1*ENSMUSG0000003841521
Foxf1 / Q61080 / Forkhead box protein F1 / Q12946* / forkhead box F1*ENSMUSG0000004281219
Gm5294 / AC187653.1*ENSMUSG0000009450418
Foxp4 / Q9DBY0 / Forkhead box protein P4 / Q8IVH2* / forkhead box P4*ENSMUSG0000002399116
Foxp2 / P58463 / Forkhead box protein P2 / O15409* / forkhead box P2*ENSMUSG0000002956316
Foxp1 / P58462 / Mus musculus forkhead box P1 (Foxp1), transcript variant 4, mRNA.ENSMUSG0000003006716
Foxh1 / O88621 / Forkhead box protein H1 / O75593* / forkhead box H1*ENSMUSG0000003383716
Gm43517ENSMUSG0000008992212
Foxp3 / Q99JB6 / Forkhead box protein P3 Forkhead box protein P3, C-terminally processed Forkhead box protein P3 41 kDa form / Q9BZS1* / forkhead box P3*ENSMUSG0000003952110


Protein motifs (from Interpro)
Interpro ID Name
 IPR001766  Fork head domain
 IPR018122  Fork head domain conserved site1
 IPR030456  Fork head domain conserved site 2
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0009653 anatomical structure morphogenesis IBA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000519 hydronephrosis "dilation of the pelvis and calices of one or both kidneys" [J:56641]
Show

Allelic Composition: Pax3Sp-1H/Pax3Sp-1H
Genetic Background: involves: 101/H * C3H/HeH * C57BL/6

Allelic Composition: Foxd2tm1Blh/Foxd2tm1Blh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0000536 hydroureter "distention of the ureter with urine, due to blockage from any cause" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:Cml, J:13044]
Show

Allelic Composition: Pax3Sp-1H/Pax3Sp-1H
Genetic Background: involves: 101/H * C3H/HeH * C57BL/6

Allelic Composition: Foxd2tm1Blh/Foxd2tm1Blh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0002989 small kidney "reduced physical bulk one or both of the organs responsible for urine secretion" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pax3Sp-1H/Pax3Sp-1H
Genetic Background: involves: 101/H * C3H/HeH * C57BL/6

Allelic Composition: Foxd2tm1Blh/Foxd2tm1Blh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0002990 short ureter "reduced length of the tube that conducts the urine from the renal pelvis to the bladder" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Pax3Sp-1H/Pax3Sp-1H
Genetic Background: involves: 101/H * C3H/HeH * C57BL/6

Allelic Composition: Foxd2tm1Blh/Foxd2tm1Blh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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