ENSG00000141298


Homo sapiens

Features
Gene ID: ENSG00000141298
  
Biological name :SSH2
  
Synonyms : Q76I76 / slingshot protein phosphatase 2 / SSH2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q11.2
Gene start: 29625938
Gene end: 29930276
  
Corresponding Affymetrix probe sets: 1554114_s_at (Human Genome U133 Plus 2.0 Array)   1555423_at (Human Genome U133 Plus 2.0 Array)   1555425_x_at (Human Genome U133 Plus 2.0 Array)   226080_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000468037
Ensembl peptide - ENSP00000466607
Ensembl peptide - ENSP00000467164
Ensembl peptide - ENSP00000269033
Ensembl peptide - ENSP00000444743
Ensembl peptide - ENSP00000462583
Ensembl peptide - ENSP00000462605
Ensembl peptide - ENSP00000465703
NCBI entrez gene - 85464     See in Manteia.
OMIM - 606779
RefSeq - XM_017025255
RefSeq - XM_006722149
RefSeq - XM_011525402
RefSeq - XM_011525404
RefSeq - XM_011525405
RefSeq - XM_011525406
RefSeq - XM_011525407
RefSeq - XM_017025251
RefSeq - XM_017025252
RefSeq - XM_017025253
RefSeq - XM_017025254
RefSeq - NM_001282129
RefSeq - NM_001282130
RefSeq - NM_033389
RefSeq - XM_005258058
RefSeq - XM_005258059
RefSeq Peptide - NP_001269059
RefSeq Peptide - NP_203747
RefSeq Peptide - NP_001269058
swissprot - K7EP00
swissprot - K7EQZ0
swissprot - J3KSP5
swissprot - Q76I76
swissprot - F5H527
swissprot - J3KSQ9
swissprot - K7EKN7
Ensembl - ENSG00000141298
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ssh2aENSDARG00000088440Danio rerio
 ssh2bENSDARG00000098955Danio rerio
 SSH2ENSGALG00000021572Gallus gallus
 Ssh2ENSMUSG00000037926Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SSH1 / Q8WYL5 / slingshot protein phosphatase 1ENSG0000008411231
SSH3 / Q8TE77 / slingshot protein phosphatase 3ENSG0000017283017
DUSP16 / Q9BY84 / dual specificity phosphatase 16ENSG0000011126610
DUSP8 / Q13202 / dual specificity phosphatase 8ENSG000001845459
DUSP1 / P28562 / dual specificity phosphatase 1ENSG000001201296
DUSP4 / Q13115 / dual specificity phosphatase 4ENSG000001208756
DUSP2 / Q05923 / dual specificity phosphatase 2ENSG000001580506
DUSP10 / Q9Y6W6 / dual specificity phosphatase 10ENSG000001435076
DUSP6 / Q16828 / dual specificity phosphatase 6ENSG000001393186
DUSP5 / Q16690 / dual specificity phosphatase 5ENSG000001381666
DUSP7 / Q16829 / dual specificity phosphatase 7ENSG000001640866
DUSP9 / Q99956 / dual specificity phosphatase 9ENSG000001308296


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR014876  DEK, C-terminal
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR020422  Dual specificity protein phosphatase domain
 IPR024950  Dual specificity phosphatase
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0008064 regulation of actin polymerization or depolymerization IBA
 biological_processGO:0010591 regulation of lamellipodium assembly IBA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0030036 actin cytoskeleton organization IMP
 biological_processGO:0030335 positive regulation of cell migration IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0050770 regulation of axonogenesis IBA
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005856 cytoskeleton IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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