ENSG00000084112


Homo sapiens

Features
Gene ID: ENSG00000084112
  
Biological name :SSH1
  
Synonyms : Q8WYL5 / slingshot protein phosphatase 1 / SSH1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q24.11
Gene start: 108778192
Gene end: 108857590
  
Corresponding Affymetrix probe sets: 1554274_a_at (Human Genome U133 Plus 2.0 Array)   1555624_a_at (Human Genome U133 Plus 2.0 Array)   221752_at (Human Genome U133 Plus 2.0 Array)   221753_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000448824
Ensembl peptide - ENSP00000447629
Ensembl peptide - ENSP00000448586
Ensembl peptide - ENSP00000315713
Ensembl peptide - ENSP00000326107
Ensembl peptide - ENSP00000446652
NCBI entrez gene - 54434     See in Manteia.
OMIM - 606778
RefSeq - XM_017019494
RefSeq - XM_011538497
RefSeq - XM_011538499
RefSeq - XM_011538500
RefSeq - XM_011538501
RefSeq - XM_017019491
RefSeq - XM_017019492
RefSeq - XM_017019493
RefSeq - NM_001161330
RefSeq - NM_001161331
RefSeq - NM_018984
RefSeq - XM_005268984
RefSeq - XM_005268985
RefSeq Peptide - NP_061857
RefSeq Peptide - NP_001154802
RefSeq Peptide - NP_001154803
swissprot - F8VS18
swissprot - Q8WYL5
swissprot - H0YHR3
swissprot - F8W1D9
Ensembl - ENSG00000084112
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ssh1aENSDARG00000056780Danio rerio
 ssh1bENSDARG00000010031Danio rerio
 SSH1ENSGALG00000004928Gallus gallus
 Ssh1ENSMUSG00000042121Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SSH2 / Q76I76 / slingshot protein phosphatase 2ENSG0000014129843
SSH3 / Q8TE77 / slingshot protein phosphatase 3ENSG0000017283025
DUSP16 / Q9BY84 / dual specificity phosphatase 16ENSG0000011126613
DUSP8 / Q13202 / dual specificity phosphatase 8ENSG0000018454512
DUSP7 / Q16829 / dual specificity phosphatase 7ENSG0000016408610
DUSP9 / Q99956 / dual specificity phosphatase 9ENSG0000013082910
DUSP4 / Q13115 / dual specificity phosphatase 4ENSG000001208759
DUSP1 / P28562 / dual specificity phosphatase 1ENSG000001201299
DUSP5 / Q16690 / dual specificity phosphatase 5ENSG000001381669
DUSP10 / Q9Y6W6 / dual specificity phosphatase 10ENSG000001435079
DUSP6 / Q16828 / dual specificity phosphatase 6ENSG000001393189
DUSP2 / Q05923 / dual specificity phosphatase 2ENSG000001580508


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR014876  DEK, C-terminal
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR020422  Dual specificity protein phosphatase domain
 IPR024950  Dual specificity phosphatase
 IPR027233  Protein phosphatase Slingshot homologue 1
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000902 cell morphogenesis IMP
 biological_processGO:0006470 protein dephosphorylation IMP
 biological_processGO:0008064 regulation of actin polymerization or depolymerization IBA
 biological_processGO:0010591 regulation of lamellipodium assembly IBA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0031915 positive regulation of synaptic plasticity IEA
 biological_processGO:0032268 regulation of cellular protein metabolic process IDA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0050770 regulation of axonogenesis IBA
 biological_processGO:0071318 cellular response to ATP IDA
 biological_processGO:0098976 excitatory chemical synaptic transmission IEA
 biological_processGO:1901216 positive regulation of neuron death IEA
 biological_processGO:1904719 positive regulation of AMPA glutamate receptor clustering IEA
 biological_processGO:1904754 positive regulation of vascular associated smooth muscle cell migration IEA
 biological_processGO:2000463 positive regulation of excitatory postsynaptic potential IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0030496 midbody IEA
 cellular_componentGO:0031252 cell leading edge IEA
 cellular_componentGO:0032154 cleavage furrow IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IMP
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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