ENSG00000130829


Homo sapiens

Features
Gene ID: ENSG00000130829
  
Biological name :DUSP9
  
Synonyms : dual specificity phosphatase 9 / DUSP9 / Q99956
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: q28
Gene start: 153642492
Gene end: 153651326
  
Corresponding Affymetrix probe sets: 205777_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000345853
Ensembl peptide - ENSP00000359186
NCBI entrez gene - 1852     See in Manteia.
OMIM - 300134
RefSeq - XM_011531124
RefSeq - NM_001318503
RefSeq - NM_001395
RefSeq - XM_011531123
RefSeq Peptide - NP_001305432
RefSeq Peptide - NP_001386
swissprot - Q99956
Ensembl - ENSG00000130829
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Dusp9ENSMUSG00000031383Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DUSP7 / Q16829 / dual specificity phosphatase 7ENSG0000016408655
DUSP6 / Q16828 / dual specificity phosphatase 6ENSG0000013931853
DUSP4 / Q13115 / dual specificity phosphatase 4ENSG0000012087530
DUSP5 / Q16690 / dual specificity phosphatase 5ENSG0000013816629
DUSP1 / P28562 / dual specificity phosphatase 1ENSG0000012012929
DUSP2 / Q05923 / dual specificity phosphatase 2ENSG0000015805029
DUSP8 / Q13202 / dual specificity phosphatase 8ENSG0000018454528
DUSP10 / Q9Y6W6 / dual specificity phosphatase 10ENSG0000014350727
SSH1 / Q8WYL5 / slingshot protein phosphatase 1ENSG0000008411226
DUSP16 / Q9BY84 / dual specificity phosphatase 16ENSG0000011126626
SSH3 / Q8TE77 / slingshot protein phosphatase 3ENSG0000017283023
SSH2 / Q76I76 / slingshot protein phosphatase 2ENSG0000014129822


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR001763  Rhodanese-like domain
 IPR008343  Mitogen-activated protein (MAP) kinase phosphatase
 IPR020422  Dual specificity protein phosphatase domain
 IPR024950  Dual specificity phosphatase
 IPR029021  Protein-tyrosine phosphatase-like
 IPR036873  Rhodanese-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade TAS
 biological_processGO:0000187 activation of MAPK activity TAS
 biological_processGO:0000188 inactivation of MAPK activity IEA
 biological_processGO:0006470 protein dephosphorylation TAS
 biological_processGO:0007254 JNK cascade TAS
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004721 phosphoprotein phosphatase activity TAS
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity IEA


Pathways (from Reactome)
Pathway description
RAF-independent MAPK1/3 activation
Negative regulation of MAPK pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000100030 MAPK1 / P28482 / mitogen-activated protein kinase 1  / reaction
 ENSG00000102882 MAPK3 / P27361 / mitogen-activated protein kinase 3  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr