ENSMUSG00000042121


Mus musculus

Features
Gene ID: ENSMUSG00000042121
  
Biological name :Ssh1
  
Synonyms : Protein phosphatase Slingshot homolog 1 / Q76I79 / Ssh1
  
Possible biological names infered from orthology : Q8WYL5 / slingshot protein phosphatase 1
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: F
Gene start: 113937094
Gene end: 113993894
  
Corresponding Affymetrix probe sets: 10532767 (MoGene1.0st)   1433874_at (Mouse Genome 430 2.0 Array)   1438253_at (Mouse Genome 430 2.0 Array)   1439237_a_at (Mouse Genome 430 2.0 Array)   1455854_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000107917
Ensembl peptide - ENSMUSP00000125025
Ensembl peptide - ENSMUSP00000125388
Ensembl peptide - ENSMUSP00000076873
Ensembl peptide - ENSMUSP00000124312
NCBI entrez gene - 231637     See in Manteia.
MGI - MGI:2686240
RefSeq - XM_011248193
RefSeq - NM_198109
RefSeq - XM_006530288
RefSeq Peptide - NP_932777
swissprot - E0CXT3
swissprot - Q76I79
swissprot - F8WHT2
swissprot - F7CBJ9
Ensembl - ENSMUSG00000042121
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ssh1aENSDARG00000056780Danio rerio
 ssh1bENSDARG00000010031Danio rerio
 SSH1ENSGALG00000004928Gallus gallus
 SSH1ENSG00000084112Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ssh2 / Q5SW75 / Protein phosphatase Slingshot homolog 2 / Q76I76* / slingshot protein phosphatase 2*ENSMUSG0000003792641
Ssh3 / Q8K330 / Mus musculus slingshot protein phosphatase 3 (Ssh3), transcript variant 2, mRNA. / Q8TE77* / slingshot protein phosphatase 3*ENSMUSG0000003461626
Dusp8 / O09112 / Dual specificity protein phosphatase 8 / Q13202* / dual specificity phosphatase 8*ENSMUSG0000003788712
Dusp16 / dual specificity phosphatase 16 / Q9BY84*ENSMUSG0000003020312
Dusp7 / Q91Z46 / Dual specificity protein phosphatase 7 / Q16829* / dual specificity phosphatase 7*ENSMUSG0000005371610
Dusp1 / P28563 / Dual specificity protein phosphatase 1 / P28562* / dual specificity phosphatase 1*ENSMUSG000000241909
Dusp9 / dual specificity phosphatase 9 / Q99956*ENSMUSG000000313839
Dusp5 / dual specificity phosphatase 5 / Q16690*ENSMUSG000000347659
Dusp4 / Q8BFV3 / Dual specificity protein phosphatase 4 / Q13115* / dual specificity phosphatase 4*ENSMUSG000000315309
Dusp6 / Q9DBB1 / Dual specificity protein phosphatase 6 / Q16828* / dual specificity phosphatase 6*ENSMUSG000000199609
Dusp10 / Q9ESS0 / Dual specificity protein phosphatase 10 / Q9Y6W6* / dual specificity phosphatase 10*ENSMUSG000000393849
Dusp2 / Q05922 / Dual specificity protein phosphatase 2 / Q05923* / dual specificity phosphatase 2*ENSMUSG000000273688


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR014876  DEK, C-terminal
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR020422  Dual specificity protein phosphatase domain
 IPR024950  Dual specificity phosphatase
 IPR027233  Protein phosphatase Slingshot homologue 1
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000902 cell morphogenesis ISO
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0008064 regulation of actin polymerization or depolymerization IBA
 biological_processGO:0010591 regulation of lamellipodium assembly IBA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0031915 positive regulation of synaptic plasticity IEA
 biological_processGO:0032268 regulation of cellular protein metabolic process ISO
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0050770 regulation of axonogenesis IBA
 biological_processGO:0071318 cellular response to ATP ISO
 biological_processGO:0098976 excitatory chemical synaptic transmission IEA
 biological_processGO:1901216 positive regulation of neuron death IEA
 biological_processGO:1904719 positive regulation of AMPA glutamate receptor clustering IEA
 biological_processGO:1904754 positive regulation of vascular associated smooth muscle cell migration IEA
 biological_processGO:2000463 positive regulation of excitatory postsynaptic potential IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0030496 midbody IEA
 cellular_componentGO:0031252 cell leading edge IEA
 cellular_componentGO:0032154 cleavage furrow IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0003779 actin binding IBA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity ISO
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr