ENSG00000176428


Homo sapiens

Features
Gene ID: ENSG00000176428
  
Biological name :VPS37D
  
Synonyms : Q86XT2 / VPS37D / VPS37D, ESCRT-I subunit
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q11.23
Gene start: 73667825
Gene end: 73672112
  
Corresponding Affymetrix probe sets: 235569_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000320416
Ensembl peptide - ENSP00000413337
NCBI entrez gene - 155382     See in Manteia.
OMIM - 610039
RefSeq - NM_001077621
RefSeq Peptide - NP_001071089
swissprot - C9JYT9
swissprot - Q86XT2
Ensembl - ENSG00000176428
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-284f22.3ENSDARG00000097055Danio rerio
 Q810I0ENSMUSG00000043614Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A5D8V6 / VPS37C / VPS37C, ESCRT-I subunitENSG0000016798732
Q9H9H4 / VPS37B / VPS37B, ESCRT-I subunitENSG0000013972232
Q8NEZ2 / VPS37A / VPS37A, ESCRT-I subunitENSG0000015597518


Protein motifs (from Interpro)
Interpro ID Name
 IPR009851  Modifier of rudimentary, Modr


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016197 endosomal transport TAS
 biological_processGO:0016236 macroautophagy TAS
 biological_processGO:0019058 viral life cycle TAS
 biological_processGO:0032509 endosome transport via multivesicular body sorting pathway IEA
 biological_processGO:0036258 multivesicular body assembly TAS
 biological_processGO:0039702 viral budding via host ESCRT complex TAS
 biological_processGO:0075733 intracellular transport of virus TAS
 cellular_componentGO:0000813 ESCRT I complex IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0010008 endosome membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031902 late endosome membrane IEA
 cellular_componentGO:0043657 host cell IEA
 cellular_componentGO:0070062 extracellular exosome HDA


Pathways (from Reactome)
Pathway description
Budding and maturation of HIV virion
Membrane binding and targetting of GAG proteins
Endosomal Sorting Complex Required For Transport (ESCRT)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000131475 VPS25 / Q9BRG1 / vacuolar protein sorting 25 homolog  / reaction
 ENSG00000074319 Q99816 / TSG101 / tumor susceptibility 101  / complex
 ENSG00000115145 STAM2 / O75886 / signal transducing adaptor molecule 2  / reaction
 ENSG00000159210 SNF8 / Q96H20 / SNF8, ESCRT-II complex subunit  / reaction
 ENSG00000160948 VPS28 / Q9UK41 / VPS28, ESCRT-I subunit  / complex
 ENSG00000141971 MVB12A / Q96EY5 / multivesicular body subunit 12A  / complex
 ENSG00000165006 UBAP1 / Q9NZ09 / ubiquitin associated protein 1  / complex
 ENSG00000196814 MVB12B / Q9H7P6 / multivesicular body subunit 12B  / complex
 ENSG00000185359 HGS / O14964 / hepatocyte growth factor-regulated tyrosine kinase substrate  / reaction
 ENSG00000136100 VPS36 / Q86VN1 / vacuolar protein sorting 36 homolog  / reaction
 ENSG00000136738 STAM / Q92783 / signal transducing adaptor molecule  / reaction






 

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