ENSG00000185610


Homo sapiens

Features
Gene ID: ENSG00000185610
  
Biological name :DBX2
  
Synonyms : DBX2 / developing brain homeobox 2 / Q6ZNG2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q12
Gene start: 45014672
Gene end: 45051099
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000331470
NCBI entrez gene - 440097     See in Manteia.
RefSeq - NM_001004329
RefSeq Peptide - NP_001004329
swissprot - Q6ZNG2
Ensembl - ENSG00000185610
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DBX2ENSGALG00000009604Gallus gallus
 Dbx2ENSMUSG00000045608Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DBX1 / A6NMT0 / developing brain homeobox 1ENSG0000010985135
HLX / Q14774 / H2.0 like homeoboxENSG0000013663028
HHEX / Q03014 / hematopoietically expressed homeoboxENSG0000015280418
BARX2 / Q9UMQ3 / BARX homeobox 2ENSG0000004303917
BARHL2 / Q9NY43 / BarH like homeobox 2ENSG0000014303217
BARX1 / Q9HBU1 / BARX homeobox 1ENSG0000013166817
NKX6-1 / P78426 / NK6 homeobox 1ENSG0000016362317
BARHL1 / Q9BZE3 / BarH like homeobox 1ENSG0000012549215
BSX / Q3C1V8 / brain specific homeoboxENSG0000018890915
TLX3 / O43711 / T cell leukemia homeobox 3ENSG0000016443814
NKX6-2 / Q9C056 / NK6 homeobox 2ENSG0000014882614
TLX2 / O43763 / T cell leukemia homeobox 2ENSG0000011529713
LBX1 / P52954 / ladybird homeobox 1ENSG0000013813613
TLX1 / P31314 / T cell leukemia homeobox 1ENSG0000010780713
LBX2 / Q6XYB7 / ladybird homeobox 2ENSG0000017952811
A6NJ46 / NKX6-3 / NK6 homeobox 3ENSG000001650666


Protein motifs (from Interpro)
Interpro ID Name
 IPR000047  Helix-turn-helix motif
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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