ENSG00000131668


Homo sapiens

Features
Gene ID: ENSG00000131668
  
Biological name :BARX1
  
Synonyms : BARX1 / BARX homeobox 1 / Q9HBU1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q22.32
Gene start: 93951622
Gene end: 93955372
  
Corresponding Affymetrix probe sets: 219845_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000385613
Ensembl peptide - ENSP00000253968
NCBI entrez gene - 56033     See in Manteia.
OMIM - 603260
RefSeq - NM_021570
RefSeq Peptide - NP_067545
swissprot - Q9HBU1
Ensembl - ENSG00000131668
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 barx1ENSDARG00000007407Danio rerio
 BARX1ENSGALG00000035557Gallus gallus
 Barx1ENSMUSG00000021381Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BARX2 / Q9UMQ3 / BARX homeobox 2ENSG0000004303946
BSX / Q3C1V8 / brain specific homeoboxENSG0000018890930
BARHL2 / Q9NY43 / BarH like homeobox 2ENSG0000014303226
HLX / Q14774 / H2.0 like homeoboxENSG0000013663026
BARHL1 / Q9BZE3 / BarH like homeobox 1ENSG0000012549224
DBX1 / A6NMT0 / developing brain homeobox 1ENSG0000010985124
DBX2 / Q6ZNG2 / developing brain homeobox 2ENSG0000018561023
NKX6-1 / P78426 / NK6 homeobox 1ENSG0000016362323
LBX1 / P52954 / ladybird homeobox 1ENSG0000013813622
HHEX / Q03014 / hematopoietically expressed homeoboxENSG0000015280422
TLX1 / P31314 / T cell leukemia homeobox 1ENSG0000010780721
TLX2 / O43763 / T cell leukemia homeobox 2ENSG0000011529720
TLX3 / O43711 / T cell leukemia homeobox 3ENSG0000016443820
NKX6-2 / Q9C056 / NK6 homeobox 2ENSG0000014882619
LBX2 / Q6XYB7 / ladybird homeobox 2ENSG0000017952819
A6NJ46 / NKX6-3 / NK6 homeobox 3ENSG000001650669


Protein motifs (from Interpro)
Interpro ID Name
 IPR000047  Helix-turn-helix motif
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007267 cell-cell signaling IEA
 biological_processGO:0009888 tissue development IBA
 biological_processGO:0009952 anterior/posterior pattern specification IEA
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IEA
 biological_processGO:0030855 epithelial cell differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048513 animal organ development IBA
 biological_processGO:0048536 spleen development IEA
 biological_processGO:0048856 anatomical structure development IEA
 biological_processGO:0055123 digestive system development IBA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity NAS
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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