ENSG00000043039


Homo sapiens

Features
Gene ID: ENSG00000043039
  
Biological name :BARX2
  
Synonyms : BARX2 / BARX homeobox 2 / Q9UMQ3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q24.3
Gene start: 129375940
Gene end: 129452279
  
Corresponding Affymetrix probe sets: 210419_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000281437
NCBI entrez gene - 8538     See in Manteia.
OMIM - 604823
RefSeq - NM_003658
RefSeq Peptide - NP_003649
swissprot - Q9UMQ3
Ensembl - ENSG00000043039
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 barx2ENSDARG00000041098Danio rerio
 BARX2ENSGALG00000029382Gallus gallus
 Barx2ENSMUSG00000032033Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BARX1 / Q9HBU1 / BARX homeobox 1ENSG0000013166842
BARHL2 / Q9NY43 / BarH like homeobox 2ENSG0000014303229
BARHL1 / Q9BZE3 / BarH like homeobox 1ENSG0000012549228
BSX / Q3C1V8 / brain specific homeoboxENSG0000018890926
HLX / Q14774 / H2.0 like homeoboxENSG0000013663024
LBX1 / P52954 / ladybird homeobox 1ENSG0000013813623
DBX1 / A6NMT0 / developing brain homeobox 1ENSG0000010985122
NKX6-1 / P78426 / NK6 homeobox 1ENSG0000016362322
DBX2 / Q6ZNG2 / developing brain homeobox 2ENSG0000018561020
TLX3 / O43711 / T cell leukemia homeobox 3ENSG0000016443820
TLX1 / P31314 / T cell leukemia homeobox 1ENSG0000010780720
HHEX / Q03014 / hematopoietically expressed homeoboxENSG0000015280420
TLX2 / O43763 / T cell leukemia homeobox 2ENSG0000011529719
NKX6-2 / Q9C056 / NK6 homeobox 2ENSG0000014882619
LBX2 / Q6XYB7 / ladybird homeobox 2ENSG0000017952818
A6NJ46 / NKX6-3 / NK6 homeobox 3ENSG000001650668


Protein motifs (from Interpro)
Interpro ID Name
 IPR000047  Helix-turn-helix motif
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001502 cartilage condensation IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0014902 myotube differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IMP
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IMP
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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