ENSG00000143032


Homo sapiens

Features
Gene ID: ENSG00000143032
  
Biological name :BARHL2
  
Synonyms : BARHL2 / BarH like homeobox 2 / Q9NY43
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p22.2
Gene start: 90711539
Gene end: 90717237
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000359474
NCBI entrez gene - 343472     See in Manteia.
OMIM - 605212
RefSeq - NM_020063
RefSeq Peptide - NP_064447
swissprot - Q9NY43
Ensembl - ENSG00000143032
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 barhl2ENSDARG00000104361Danio rerio
 BARHL2ENSGALG00000040069Gallus gallus
 Barhl2ENSMUSG00000034384Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BARHL1 / Q9BZE3 / BarH like homeobox 1ENSG0000012549251
TLX3 / O43711 / T cell leukemia homeobox 3ENSG0000016443821
BARX2 / Q9UMQ3 / BARX homeobox 2ENSG0000004303921
TLX1 / P31314 / T cell leukemia homeobox 1ENSG0000010780719
TLX2 / O43763 / T cell leukemia homeobox 2ENSG0000011529719
BARX1 / Q9HBU1 / BARX homeobox 1ENSG0000013166817
LBX1 / P52954 / ladybird homeobox 1ENSG0000013813617
HLX / Q14774 / H2.0 like homeoboxENSG0000013663017
BSX / Q3C1V8 / brain specific homeoboxENSG0000018890916
DBX1 / A6NMT0 / developing brain homeobox 1ENSG0000010985115
DBX2 / Q6ZNG2 / developing brain homeobox 2ENSG0000018561015
NKX6-1 / P78426 / NK6 homeobox 1ENSG0000016362315
HHEX / Q03014 / hematopoietically expressed homeoboxENSG0000015280414
NKX6-2 / Q9C056 / NK6 homeobox 2ENSG0000014882614
LBX2 / Q6XYB7 / ladybird homeobox 2ENSG0000017952814
A6NJ46 / NKX6-3 / NK6 homeobox 3ENSG000001650666


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001709 cell fate determination IEA
 biological_processGO:0001764 neuron migration IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0030182 neuron differentiation IEA
 biological_processGO:0030516 regulation of axon extension IEA
 biological_processGO:0045165 cell fate commitment IEA
 biological_processGO:0045727 positive regulation of translation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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