ENSG00000164438


Homo sapiens

Features
Gene ID: ENSG00000164438
  
Biological name :TLX3
  
Synonyms : O43711 / T cell leukemia homeobox 3 / TLX3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q35.1
Gene start: 171309284
Gene end: 171312134
  
Corresponding Affymetrix probe sets: 208495_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000296921
NCBI entrez gene - 30012     See in Manteia.
OMIM - 604640
RefSeq - NM_021025
RefSeq Peptide - NP_066305
swissprot - O43711
Ensembl - ENSG00000164438
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Tlx3ENSMUSG00000040610Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TLX1 / P31314 / T cell leukemia homeobox 1ENSG0000010780766
TLX2 / O43763 / T cell leukemia homeobox 2ENSG0000011529761
BARHL2 / Q9NY43 / BarH like homeobox 2ENSG0000014303228
BARHL1 / Q9BZE3 / BarH like homeobox 1ENSG0000012549224
NKX6-1 / P78426 / NK6 homeobox 1ENSG0000016362323
HHEX / Q03014 / hematopoietically expressed homeoboxENSG0000015280422
NKX6-2 / Q9C056 / NK6 homeobox 2ENSG0000014882622
LBX1 / P52954 / ladybird homeobox 1ENSG0000013813621
DBX1 / A6NMT0 / developing brain homeobox 1ENSG0000010985121
BARX2 / Q9UMQ3 / BARX homeobox 2ENSG0000004303920
LBX2 / Q6XYB7 / ladybird homeobox 2ENSG0000017952820
HLX / Q14774 / H2.0 like homeoboxENSG0000013663020
BARX1 / Q9HBU1 / BARX homeobox 1ENSG0000013166818
BSX / Q3C1V8 / brain specific homeoboxENSG0000018890917
DBX2 / Q6ZNG2 / developing brain homeobox 2ENSG0000018561016
A6NJ46 / NKX6-3 / NK6 homeobox 3ENSG000001650666


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001708 cell fate specification IEA
 biological_processGO:0001764 neuron migration IEA
 biological_processGO:0002087 regulation of respiratory gaseous exchange by neurological system process IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007417 central nervous system development IEA
 biological_processGO:0007585 respiratory gaseous exchange IEA
 biological_processGO:0030182 neuron differentiation IEA
 biological_processGO:0045665 negative regulation of neuron differentiation IEA
 biological_processGO:0048665 neuron fate specification IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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