ENSGALG00000000726


Gallus gallus

Features
Gene ID: ENSGALG00000000726
  
Biological name :ELAVL1
  
Synonyms : ELAVL1 / ELAV-like protein 1
  
Possible biological names infered from orthology : ELAV like RNA binding protein 1 / P70372 / Q15717
  
Species: Gallus gallus
  
Chr. number: 28
Strand: -1
Band:
Gene start: 919939
Gene end: 942567
  
Corresponding Affymetrix probe sets: Gga.1877.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000061925
Ensembl peptide - ENSGALP00000001027
NCBI entrez gene - 395637     See in Manteia.
RefSeq - XM_015299671
RefSeq - XM_015299668
RefSeq - XM_015299669
RefSeq - XM_015299670
RefSeq - NM_204833
RefSeq - XM_015299666
RefSeq - XM_015299667
RefSeq Peptide - NP_990164
swissprot - F1N9I5
swissprot - A0A1L1RSY4
Ensembl - ENSGALG00000000726
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 elavl1aENSDARG00000038695Danio rerio
 elavl1bENSDARG00000101744Danio rerio
 ELAVL1ENSG00000066044Homo sapiens
 Elavl1ENSMUSG00000040028Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ELAVL2 / ELAV like RNA binding protein 2 / Q12926* / Q60899* / Mus musculus ELAV like RNA binding protein 1 (Elavl2), transcript variant 5, mRNA.*ENSGALG0000001579973
ELAVL4 / ELAV-like protein 4 / P26378* / Q61701* / ELAV like RNA binding protein 4* / Mus musculus ELAV like RNA binding protein 4 (Elavl4), transcript variant 5, mRNA.*ENSGALG0000001053372
RBMS1 / RNA binding motif single stranded interacting protein 1 / P29558* / Q91W59*ENSGALG0000001113226
RBMS2 / RNA binding motif single stranded interacting protein 2 / Q15434* / Q8VC70*ENSGALG0000003875724
PUF60 / poly(U)-binding-splicing factor PUF60 / Q3UEB3* / Q9UHX1* / poly(U) binding splicing factor 60*ENSGALG0000003990123
Q13310* / P0CB38* / PABPC4* / PABPC4L* / poly(A) binding protein cytoplasmic 4* / poly(A) binding protein cytoplasmic 4 like*ENSGALG0000000380023
PABPC1 / polyadenylate-binding protein 1 / PABPC3* / Q9H361* / P11940* / P29341* / poly(A) binding protein cytoplasmic 3* / poly(A) binding protein cytoplasmic 1*ENSGALG0000003028022
PABPC1L / poly(A) binding protein cytoplasmic 1 like / Q4VXU2*ENSGALG0000000412320
RBMS3 / RNA binding motif single stranded interacting protein 3 / Q6XE24* / Q8BWL5* / RNA binding motif, single stranded interacting protein*ENSGALG0000001143919
ENSGALG000000382599


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR002343  Paraneoplastic encephalomyelitis antigen
 IPR006548  Splicing factor ELAV/Hu
 IPR012677  Nucleotide-binding alpha-beta plait domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0045727 positive regulation of translation IEA
 biological_processGO:0048255 mRNA stabilization IEA
 biological_processGO:0060965 negative regulation of gene silencing by miRNA IEA
 biological_processGO:0070935 3"-UTR-mediated mRNA stabilization IEA
 biological_processGO:2000036 regulation of stem cell population maintenance IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:1990904 ribonucleoprotein complex IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003725 double-stranded RNA binding IEA
 molecular_functionGO:0003729 mRNA binding IEA
 molecular_functionGO:0003730 mRNA 3"-UTR binding IEA
 molecular_functionGO:0017091 AU-rich element binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0035925 mRNA 3"-UTR AU-rich region binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
HuR (ELAVL1) binds and stabilizes mRNA
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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