ENSGALG00000003928


Gallus gallus

Features
Gene ID: ENSGALG00000003928
  
Biological name :LHX3
  
Synonyms : LHX3 / LIM/homeobox protein Lhx3
  
Possible biological names infered from orthology : LIM homeobox 3 / LIM homeobox protein 3 / P50481 / Q9UBR4
  
Species: Gallus gallus
  
Chr. number: 17
Strand: 1
Band:
Gene start: 8530009
Gene end: 8535525
  
Corresponding Affymetrix probe sets: Gga.91.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000002660
NCBI entrez gene - 373940     See in Manteia.
RefSeq - NM_001030335
RefSeq - XM_015279253
RefSeq Peptide - NP_001025506
swissprot - A0A1I7Q3Y6
Ensembl - ENSGALG00000003928
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LHX3ENSDARG00000003803Danio rerio
 LHX3ENSG00000107187Homo sapiens
 Lhx3ENSMUSG00000026934Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LHX4 / LIM homeobox 4 / P53776* / Q969G2* / LIM/homeobox protein Lhx4 *ENSGALG0000003658766
LHX5 / Gallus gallus LIM homeobox 5 (LHX5), mRNA. / P61375* / Q9H2C1* / LIM homeobox 5* / LIM homeobox protein 5*ENSGALG0000000830339
LHX1 / LIM/homeobox protein Lhx1 / P48742* / P63006* / LIM homeobox 1*ENSGALG0000000540937
LMX1A / LIM homeobox transcription factor 1 alpha / Q8TE12* / Q9JKU8*ENSGALG0000000342431
LMX1B / P53413 / LIM/homeobox protein LMX-1.2 / O60663* / LIM homeobox transcription factor 1 beta*ENSGALG0000004058229
ISL1 / P50211 / Insulin gene enhancer protein ISL-1 / P61372* / P61371* / ISL LIM homeobox 1* / Insulin enhancer protein ISL-1 *ENSGALG0000001488425
LHX8 / LIM/homeobox protein Lhx8 / O35652* / Q68G74* / LIM homeobox 8*ENSGALG0000001136924
LHX6 / LIM homeobox 6 / Q9R1R0* / Q9UPM6* / Mus musculus LIM homeobox protein 6 (Lhx6), transcript variant 5, mRNA.*ENSGALG0000000134724
LHX2 / LIM/homeobox protein Lhx2 ENSGALG0000000112423
LHX9 / LIM/homeobox protein Lhx9 / Q9NQ69* / Q9WUH2* / LIM homeobox 9*ENSGALG0000000222323
ISL2 / ISL LIM homeobox 2 / Q96A47* / Q9CXV0* / Insulin enhancer protein ISL-2 *ENSGALG0000003339118
LMO4 / LIM domain only 4 / P61968* / P61969* / LIM domain transcription factor LMO4 *ENSGALG0000000625215
ENSGALG0000003567914
LMO3 / LIM domain only 3 / Q8BZL8* / Q8TAP4* / Mus musculus LIM domain only 3 (Lmo3), transcript variant 2, mRNA.*ENSGALG0000003635814
LMO2 / LIM domain only 2 / P25791* / P25801* / Rhombotin-2 *ENSGALG0000002989211


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR001781  Zinc finger, LIM-type
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001890 placenta development IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0008045 motor neuron axon guidance IEA
 biological_processGO:0009953 dorsal/ventral pattern formation IEA
 biological_processGO:0021520 spinal cord motor neuron cell fate specification IEA
 biological_processGO:0021521 ventral spinal cord interneuron specification IEA
 biological_processGO:0021526 medial motor column neuron differentiation IEA
 biological_processGO:0021527 spinal cord association neuron differentiation IEA
 biological_processGO:0021983 pituitary gland development IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048839 inner ear development IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001076 transcription factor activity, RNA polymerase II transcription factor binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001085 RNA polymerase II transcription factor binding IEA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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