ENSGALG00000003424


Gallus gallus

Features
Gene ID: ENSGALG00000003424
  
Biological name :LMX1A
  
Synonyms : LIM homeobox transcription factor 1 alpha / LMX1A
  
Possible biological names infered from orthology : Q8TE12 / Q9JKU8
  
Species: Gallus gallus
  
Chr. number: 8
Strand: 1
Band:
Gene start: 5172828
Gene end: 5196196
  
Corresponding Affymetrix probe sets: GgaAffx.2124.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000005401
NCBI entrez gene - 777133     See in Manteia.
RefSeq - NM_001257388
RefSeq - XM_015290334
RefSeq Peptide - NP_001244317
swissprot - E1C2D6
Ensembl - ENSGALG00000003424
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lmx1aENSDARG00000020354Danio rerio
 LMX1AENSG00000162761Homo sapiens
 Lmx1aENSMUSG00000026686Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LMX1B / P53413 / LIM/homeobox protein LMX-1.2 / O60663* / LIM homeobox transcription factor 1 beta*ENSGALG0000004058266
LHX5 / Gallus gallus LIM homeobox 5 (LHX5), mRNA. / P61375* / Q9H2C1* / LIM homeobox 5* / LIM homeobox protein 5*ENSGALG0000000830333
LHX3 / LIM/homeobox protein Lhx3 / Q9UBR4* / P50481* / LIM homeobox 3* / LIM homeobox protein 3*ENSGALG0000000392832
LHX1 / LIM/homeobox protein Lhx1 / P48742* / P63006* / LIM homeobox 1*ENSGALG0000000540932
LHX4 / LIM homeobox 4 / P53776* / Q969G2* / LIM/homeobox protein Lhx4 *ENSGALG0000003658728
ISL1 / P50211 / Insulin gene enhancer protein ISL-1 / P61372* / P61371* / ISL LIM homeobox 1* / Insulin enhancer protein ISL-1 *ENSGALG0000001488427
LHX8 / LIM/homeobox protein Lhx8 / O35652* / Q68G74* / LIM homeobox 8*ENSGALG0000001136926
LHX9 / LIM/homeobox protein Lhx9 / Q9NQ69* / Q9WUH2* / LIM homeobox 9*ENSGALG0000000222326
LHX6 / LIM homeobox 6 / Q9R1R0* / Q9UPM6* / Mus musculus LIM homeobox protein 6 (Lhx6), transcript variant 5, mRNA.*ENSGALG0000000134725
LHX2 / LIM/homeobox protein Lhx2 ENSGALG0000000112424
ISL2 / ISL LIM homeobox 2 / Q96A47* / Q9CXV0* / Insulin enhancer protein ISL-2 *ENSGALG0000003339119
LMO4 / LIM domain only 4 / P61968* / P61969* / LIM domain transcription factor LMO4 *ENSGALG0000000625218
ENSGALG0000003567915
LMO3 / LIM domain only 3 / Q8BZL8* / Q8TAP4* / Mus musculus LIM domain only 3 (Lmo3), transcript variant 2, mRNA.*ENSGALG0000003635815
LMO2 / LIM domain only 2 / P25791* / P25801* / Rhombotin-2 *ENSGALG0000002989212


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR001781  Zinc finger, LIM-type
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001558 regulation of cell growth IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0007417 central nervous system development IEA
 biological_processGO:0007613 memory IEA
 biological_processGO:0007626 locomotory behavior IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0021542 dentate gyrus development IEA
 biological_processGO:0021549 cerebellum development IEA
 biological_processGO:0021766 hippocampus development IEA
 biological_processGO:0021953 central nervous system neuron differentiation IEA
 biological_processGO:0030182 neuron differentiation IEA
 biological_processGO:0030901 midbrain development IEA
 biological_processGO:0042048 olfactory behavior IEA
 biological_processGO:0045665 negative regulation of neuron differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0050808 synapse organization IEA
 biological_processGO:0071542 dopaminergic neuron differentiation IEA
 biological_processGO:1904948 midbrain dopaminergic neuron differentiation IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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