ENSGALG00000006312


Gallus gallus

Features
Gene ID: ENSGALG00000006312
  
Biological name :TSG101
  
Synonyms : TSG101 / tumor susceptibility 101
  
Possible biological names infered from orthology : Q61187 / Q99816 / tumor susceptibility gene 101
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 12561863
Gene end: 12575762
  
Corresponding Affymetrix probe sets: Gga.9332.1.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000049617
Ensembl peptide - ENSGALP00000064118
Ensembl peptide - ENSGALP00000059620
Ensembl peptide - ENSGALP00000010193
NCBI entrez gene - 423082     See in Manteia.
RefSeq - NM_001277415
RefSeq - XM_015286583
RefSeq Peptide - NP_001264344
swissprot - E1BWW2
swissprot - A0A1D5PA57
Ensembl - ENSGALG00000006312
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tsg101aENSDARG00000040854Danio rerio
 tsg101bENSDARG00000011897Danio rerio
 Q99816ENSG00000074319Homo sapiens
 Q61187ENSMUSG00000014402Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008883  Ubiquitin E2 variant, N-terminal
 IPR016135  Ubiquitin-conjugating enzyme/RWD-like
 IPR017916  Steadiness box (SB) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001558 regulation of cell growth IEA
 biological_processGO:0006464 cellular protein modification process IEA
 biological_processGO:0006858 extracellular transport IEA
 biological_processGO:0007050 cell cycle arrest IEA
 biological_processGO:0007175 negative regulation of epidermal growth factor-activated receptor activity IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030216 keratinocyte differentiation IEA
 biological_processGO:0042059 negative regulation of epidermal growth factor receptor signaling pathway IEA
 biological_processGO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway IEA
 biological_processGO:0043405 regulation of MAP kinase activity IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0046755 viral budding IEA
 biological_processGO:0048524 positive regulation of viral process IEA
 biological_processGO:1902188 positive regulation of viral release from host cell IEA
 biological_processGO:1903543 positive regulation of exosomal secretion IEA
 biological_processGO:1903551 regulation of extracellular exosome assembly IEA
 biological_processGO:1903772 regulation of viral budding via host ESCRT complex IEA
 biological_processGO:1903774 positive regulation of viral budding via host ESCRT complex IEA
 biological_processGO:1990182 exosomal secretion IEA
 biological_processGO:2000397 positive regulation of ubiquitin-dependent endocytosis IEA
 cellular_componentGO:0000813 ESCRT I complex IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0070062 extracellular exosome IEA
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0043130 ubiquitin binding IEA
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0046790 virion binding IEA
 molecular_functionGO:0048306 calcium-dependent protein binding IEA


Pathways (from Reactome)
Pathway description
Endosomal Sorting Complex Required For Transport (ESCRT)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001309 SNF8 / SNF8, ESCRT-II complex subunit / Q96H20* / Q9CZ28* / Mus musculus SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) (Snf8), transcript variant 2, mRNA.*  / reaction
 ENSGALG00000003743 VPS37B / VPS37B, ESCRT-I subunit / Q8R0J7* / Q9H9H4* / vacuolar protein sorting 37B*  / complex
 ENSGALG00000000950 MVB12B / multivesicular body subunit 12B / Q6KAU4* / Q9H7P6*  / complex
 ENSGALG00000007224 HGS / hepatocyte growth factor-regulated tyrosine kinase substrate / O14964* / hepatocyte growth factor-regulated tyrosine kinase substrate isoform 2 *  / reaction
 ENSGALG00000013646 VPS37A / VPS37A, ESCRT-I subunit / Q8CHS8* / Q8NEZ2* / vacuolar protein sorting 37A*  / complex
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / complex / reaction
 ENSGALG00000035287 STAM / signal transducing adaptor molecule / P70297* / Q92783* / signal transducing adaptor molecule (SH3 domain and ITAM motif) 1*  / reaction
 ENSGALG00000038541 VPS37C / vacuolar protein sorting-associated protein 37C / Q8R105* / A5D8V6* / VPS37C, ESCRT-I subunit* / vacuolar protein sorting 37C*  / complex
 ENSGALG00000034262 VPS25 / vacuolar protein sorting 25 homolog / Q9BRG1* / Q9CQ80* / vacuolar protein sorting 25*  / reaction
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / complex / reaction






 

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