ENSGALG00000007579


Gallus gallus

Features
Gene ID: ENSGALG00000007579
  
Biological name :APBB1IP
  
Synonyms : amyloid beta precursor protein binding family B member 1 interacting protein / APBB1IP
  
Possible biological names infered from orthology : amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein / Q7Z5R6 / Q8R5A3
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 16147118
Gene end: 16204934
  
Corresponding Affymetrix probe sets: Gga.7334.1.S1_at (Chicken Array)   GgaAffx.12014.1.S1_s_at (Chicken Array)   GgaAffx.22287.1.S1_s_at (Chicken Array)   GgaAffx.22287.2.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000012240
Ensembl peptide - ENSGALP00000054162
NCBI entrez gene - 420492     See in Manteia.
RefSeq - NM_001006357
RefSeq Peptide - NP_001006357
swissprot - E1BZU4
swissprot - A0A1D5PMS5
Ensembl - ENSGALG00000007579
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 apbb1ipENSDARG00000016505Danio rerio
 Q7Z5R6ENSG00000077420Homo sapiens
 Q8R5A3ENSMUSG00000026786Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GRB10 / growth factor receptor bound protein 10 / Q13322* / Q60760*ENSGALG0000001310019
GRB14 / growth factor receptor bound protein 14 / Q14449* / Q9JLM9*ENSGALG0000002070318
GRB7 / growth factor receptor bound protein 7 / Q03160* / Q14451*ENSGALG0000003650018
RAPH1* / Q70E73* / Ras association (RalGDS/AF-6) and pleckstrin homology domains 1*ENSGALG0000003168817


Protein motifs (from Interpro)
Interpro ID Name
 IPR000159  Ras-associating (RA) domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0045785 positive regulation of cell adhesion IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0042101 T cell receptor complex IEA


Pathways (from Reactome)
Pathway description
Integrin alphaIIb beta3 signaling
GRB2:SOS provides linkage to MAPK signaling for Integrins
p130Cas linkage to MAPK signaling for integrins
MAP2K and MAPK activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000379 ITGB3 / P05106* / O54890* / AC068234.1* / Integrin beta-3 * / integrin subunit beta 3*  / complex / reaction
 ENSGALG00000001476 RAP1A / RAP1A, member of RAS oncogene family / P62834* / P62835* / RAS-related protein 1a*  / complex / reaction
 ENSGALG00000003855 SRC / P00523 / Proto-oncogene tyrosine-protein kinase Src / P12931* / P05480* / Neuronal proto-onco tyrosine-protein kinase Src * / SRC proto-oncogene, non-receptor tyrosine kinase*  / reaction / complex
 ENSGALG00000008010 PTPN1 / tyrosine-protein phosphatase non-receptor type 1 / P18031* / P35821* / protein tyrosine phosphatase, non-receptor type 1*  / reaction
 ENSGALG00000039775 SHC1 / SHC adaptor protein 1 / P29353* / P98083* / SHC-transforming protein 1 *  / complex / reaction
 ENSGALG00000031270 CSK / tyrosine-protein kinase CSK / P41240* / P41241* / C-terminal Src kinase*  / reaction / complex
 ENSGALG00000002656 CRK / Q04929 / Adapter molecule crk / P46108* / Q64010* / CRK proto-oncogene, adaptor protein*  / reaction / complex
 ENSGALG00000009268 FGG / fibrinogen gamma chain / P02679* / Q8VCM7*  / reaction / complex
 ENSGALG00000042895 BCAR1 / BCAR1, Cas family scaffolding protein / P56945* / Q61140* / Breast cancer anti-estrogen resistance protein 1 *  / complex / reaction
 ENSGALG00000002548 TLN1 / talin-1 / P26039* / Q9Y490*  / reaction / complex
 ENSGALG00000003578 FN1 / fibronectin 1 / P02751* / P11276* / Fibronectin Anastellin*  / reaction / complex
 ENSGALG00000005079 VCL / P12003 / Vinculin / P18206* / Q64727*  / complex
 ENSGALG00000009262 FGB / fibrinogen beta chain / P02675* / Q8K0E8* / Fibrinogen beta chain Fibrinopeptide B Fibrinogen beta chain*  / reaction / complex
 ENSGALG00000031741 PTK2 / Q00944 / Focal adhesion kinase 1 / P34152* / Q05397* / protein tyrosine kinase 2* / PTK2 protein tyrosine kinase 2*  / complex / reaction
 ENSGALG00000039450 SOS1 / SOS Ras/Rac guanine nucleotide exchange factor 1 / Q07889* / Q62245* / Son of sevenless homolog 1 *  / complex / reaction
 ENSGALG00000015216 SYK / F1N9Y5 / Tyrosine-protein kinase SYK / P48025* / P43405* / spleen tyrosine kinase* / spleen associated tyrosine kinase*  / complex / reaction
 ENSGALG00000008016 GRB2 / growth factor receptor-bound protein 2 / P62993* / Q60631*  / complex / reaction
 ENSGALG00000009927 RAP1B / Q5ZHX1 / Ras-related protein Rap-1b / Q99JI6* / P61224* / RAS related protein 1b* / RAP1B, member of RAS oncogene family*  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr