ENSGALG00000007690


Gallus gallus

Features
Gene ID: ENSGALG00000007690
  
Biological name :TFAP2C
  
Synonyms : TFAP2C / transcription factor AP-2 gamma
  
Possible biological names infered from orthology : Q61312 / Q92754
  
Species: Gallus gallus
  
Chr. number: 20
Strand: -1
Band:
Gene start: 12148972
Gene end: 12156390
  
Corresponding Affymetrix probe sets: GgaAffx.22330.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000012451
NCBI entrez gene - 419327     See in Manteia.
RefSeq - XM_417497
swissprot - E1C5K7
Ensembl - ENSGALG00000007690
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tfap2cENSDARG00000040606Danio rerio
 Q92754ENSG00000087510Homo sapiens
 Q61312ENSMUSG00000028640Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TFAP2A / transcription factor AP-2-alpha / P05549*ENSGALG0000001277565
TFAP2B / transcription factor AP-2-beta / Q61313* / Q92481*ENSGALG0000001668062
TFAP2E / transcription factor AP-2 epsilon / Q6VUC0* / Q6VUP9*ENSGALG0000003949759
TFAP2D / transcription factor AP-2-delta / Q7Z6R9* / Q91ZK0*ENSGALG0000001984247


Protein motifs (from Interpro)
Interpro ID Name
 IPR004979  Transcription factor AP-2
 IPR013854  Transcription factor AP-2, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0008584 male gonad development IEA
 biological_processGO:0040029 regulation of gene expression, epigenetic IEA
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048856 anatomical structure development IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0001047 core promoter binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
SUMOylation of transcription factors
Negative regulation of activity of TFAP2 (AP-2) family transcription factors
Activation of the TFAP2 (AP-2) family of transcription factors
TFAP2 (AP-2) family regulates transcription of cell cycle factors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000678 CITED4 / Q9I8K7 / Cbp/p300-interacting transactivator 3 / Q96RK1* / Q9WUL8* / Cbp/p300-interacting transactivator 4 * / Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-termin...  / complex / reaction
 ENSGALG00000008435 SUMO1 / Q8QGH2 / Small ubiquitin-related modifier 1 / P63166* / P63165* / small ubiquitin-like modifier 1*  / reaction / complex
 ENSGALG00000007690 TFAP2C / transcription factor AP-2 gamma / Q61312* / Q92754*  / reaction / complex
 ENSGALG00000038948 KDM5B / Q5F3R2 / Lysine-specific demethylase 5B / Q80Y84* / Q9UGL1* / lysine demethylase 5B*  / complex / reaction
 ENSGALG00000006428 UBE2I / P63283 / SUMO-conjugating enzyme UBC9 / P63280* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction
 ENSGALG00000015124 KCTD1 / potassium channel tetramerization domain containing 1 / Q5M956* / Q719H9* / BTB/POZ domain-containing protein KCTD1 *  / reaction / complex
 ENSGALG00000013818 CITED2 / Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 / O35740* / Q99967* / Cbp/p300-interacting transactivator 2 *  / reaction / complex
 ENSGALG00000011992 EP300 / E1A binding protein p300 / B2RWS6* / Q09472* / Histone acetyltransferase p300 *  / complex / reaction
 ENSGALG00000033631 MYC / P01109 / Myc proto-oncogene protein / Bmyc* / Q6P8Z1* / P01106* / P01108* / Protein B-Myc * / myelocytomatosis oncogene* / MYC proto-oncogene, bHLH transcription factor*  / complex / reaction






 

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