ENSGALG00000015326


Gallus gallus

Features
Gene ID: ENSGALG00000015326
  
Biological name :CLTA
  
Synonyms : clathrin light chain A / CLTA
  
Possible biological names infered from orthology : P09496
  
Species: Gallus gallus
  
Chr. number: Z
Strand: 1
Band:
Gene start: 52040364
Gene end: 52055154
  
Corresponding Affymetrix probe sets: Gga.4834.2.S1_at (Chicken Array)   Gga.4834.3.S1_at (Chicken Array)   GgaAffx.13170.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000024691
NCBI entrez gene - 427284     See in Manteia.
RefSeq - XM_015280417
RefSeq - NM_001039313
RefSeq - XM_015280418
RefSeq Peptide - NP_001034402
swissprot - Q5ZHR7
Ensembl - ENSGALG00000015326
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cltaENSDARG00000045618Danio rerio
 CLTAENSG00000122705Homo sapiens
 CltaENSMUSG00000028478Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CLTB / clathrin light chain B / P09497* / Q6IRU5*ENSGALG0000000334458


Protein motifs (from Interpro)
Interpro ID Name
 IPR000996  Clathrin light chain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0048268 clathrin coat assembly IEA
 biological_processGO:0072583 clathrin-dependent endocytosis IBA
 cellular_componentGO:0005905 clathrin-coated pit IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030118 clathrin coat IEA
 cellular_componentGO:0030125 clathrin vesicle coat IBA
 cellular_componentGO:0030130 clathrin coat of trans-Golgi network vesicle IEA
 cellular_componentGO:0030132 clathrin coat of coated pit IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0071439 clathrin complex IEA
 molecular_functionGO:0005198 structural molecule activity IBA
 molecular_functionGO:0032050 clathrin heavy chain binding IEA


Pathways (from Reactome)
Pathway description
Retrograde neurotrophin signalling
Gap junction degradation
Formation of annular gap junctions
MHC class II antigen presentation
EPH-ephrin mediated repulsion of cells
Lysosome Vesicle Biogenesis
Golgi Associated Vesicle Biogenesis
Recycling pathway of L1
WNT5A-dependent internalization of FZD2, FZD5 and ROR2
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
VLDLR internalisation and degradation
LDL clearance


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000003344 CLTB / clathrin light chain B / P09497* / Q6IRU5*  / complex
 ENSGALG00000004594 CD74 / CD74 molecule / P04233* / P04441* / CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)*  / complex
 ENSGALG00000005139 CLTC / clathrin heavy chain / Q00610*  / reaction / complex
 ENSGALG00000008432 AP2M1 / Q5ZMP6 / AP-2 complex subunit mu / P84091* / Q96CW1* / adaptor related protein complex 2 mu 1 subunit*  / complex / reaction
 ENSGALG00000001501 MAPK1 / mitogen-activated protein kinase 1 / P28482* / P63085* / Mus musculus mitogen-activated protein kinase 1 (Mapk1), transcript variant 3, mRNA.*  / reaction / complex
 ENSGALG00000042125 AP2B1 / adaptor related protein complex 2 beta 1 subunit / P63010* / Q9DBG3* / AP-2 complex subunit beta *  / reaction / complex
 ENSGALG00000016551 AP1S2 / AP-1 complex subunit sigma-2 / P56377* / Q9DB50* / adaptor related protein complex 1 sigma 2 subunit*  / complex
 ENSGALG00000015096 Q8AXV1 / SH3GL2 / Endophilin-A1 / Q99962* / Q62420* / SH3-domain GRB2-like 2* / SH3 domain containing GRB2 like 2, endophilin A1*  / complex / reaction
 ENSGALG00000010166 VLDLR / P98165 / Very low-density lipoprotein receptor / P98155* / P98156*  / complex
 ENSGALG00000002556 NGF / nerve growth factor / P01138* / P01139* / Beta-nerve growth factor *  / complex
 ENSGALG00000015326 CLTA / clathrin light chain A / P09496*  / reaction / complex
 ENSGALG00000019019 NTRK1 / high affinity nerve growth factor receptor precursor / P04629* / Q3UFB7* / neurotrophic receptor tyrosine kinase 1* / High affinity nerve growth factor receptor *  / complex
 ENSGALG00000042213 AP1B1 / adaptor related protein complex 1 beta 1 subunit / O35643* / Q10567* / Mus musculus adaptor protein complex AP-1, beta 1 subunit (Ap1b1), transcript variant 4, mRNA.*  / complex
 ENSGALG00000005171 AP1S3 / adaptor related protein complex 1 sigma 3 subunit / Q7TN05* / Q96PC3* / AP-1 complex subunit sigma-3 *  / complex
 ENSGALG00000043451 DNAL4 / dynein axonemal light chain 4 / O96015* / Q9DCM4* / Dynein light chain 4, axonemal *  / reaction






 

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