MP:0000010 | abnormal abdominal fat pads | "malformed or aberrant size of the encapsulated adipose tissue in the abdomen" [J:65146] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0000601 | small liver | "reduced size of the liver" [J:23170] |
Show
Allelic Composition: Lamb3tm1b(KOMP)Wtsi/Lamb3tm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Lamb3tm1b(KOMP)Wtsi/H
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MP:0000642 | enlarged adrenal glands | "increased size of the endocrine gland" [J:40203] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0000664 | small coagulating gland | "reduced size of the coagulating gland" [J:64981] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0000671 | bulbourethral gland hypoplasia | "decreased cell number in the bulbourethral gland" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54465] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0000691 | enlarged spleen | "increased spleen size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0000692 | small spleen | "decreased spleen size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Lamb3tm1b(KOMP)Wtsi/Lamb3tm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Lamb3tm1b(KOMP)Wtsi/H
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MP:0000706 | small thymus | "reduced size of the thymus" [J:36561, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:31167] |
Show
Allelic Composition: Lamb3tm1b(KOMP)Wtsi/Lamb3tm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Lamb3tm1b(KOMP)Wtsi/H
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MP:0000774 | reduced brain size | "smaller appearance of the brain" [J:35802] |
Show
Allelic Composition: Lamb3tm1b(KOMP)Wtsi/Lamb3tm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Lamb3tm1b(KOMP)Wtsi/H
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MP:0001119 | abnormal female reproductive anatomy | "anomalous structure of the organs associated with producing offspring in the gender that bears the offspring" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0001120 | abnormal uterus morphology | "malformation or absence of the female muscular organ of gestation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0001126 | abnormal ovary morphology | "malformed female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0001127 | small ovary | "reduced size of the female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0001129 | impaired ovarian folliculogenesis | "a block in the formation of the spherical ovum in the ovary" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0001132 | absent mature ovarian follicles | "failure of ovarian follicle differentiation" [J:35782] |
Show
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0001134 | absent corpora lutea | "missing yellow endocrine body formed in the ovary after follicle rupture" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0001142 | abnormal vaginal opening | "a malformed or absent opening to the genital canal" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0001145 | abnormal male reproductive anatomy | "anomalous structure of the organs associated with producing offspring in the gender that produces spermatozoa" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0001147 | small testis | "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0001152 | Leydig cell hyperplasia | "increased number of interstitial cells of the seminiferous tubules that secrete testosterone" [J:45065] |
Show
Allelic Composition: Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb,Tbx1tm6(cre)Bld/Tbx1+,Tg(Pax2-cre)1Akg/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0001153 | small seminiferous tubules | "reduced diameter of the tubules in the testes where spermatogenesis occurs" [J:50844] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0001155 | arrest of spermatogenesis | "block of the process by which spermatogonial stem cells divide and differentiate into spermatozoa" [J:62271] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0001157 | small seminal gland | "reduced size, compared to the norm, of one of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0001158 | abnormal prostate morphology | "mallformed gland in males that secretes part of the seminiferous fluid" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:63764] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0001260 | increased body weight | "greater than normal average weight " [J:33400] |
Show
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0001378 | abnormal ejaculation | "anomalies in the ability to propulse semen from the genital ducts and the urethra to the exterior" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0001750 | increased circulating follicle stimulating hormone level | "higher than normal levels in the blood stream of FSH, the hormone that, in females, stimulates the graafian follicles of the ovary and assists in follicular maturation and the secretion of estradiol; in the male it stimulates the epithelium of the seminiferous tubules and is partly responsible for spermatogenesis " [J:35782, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
Allelic Composition: Lhcgrtm1Zmlei/Lhcgr+ Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0001751 | increased circulating luteinizing hormone level | "higher than the normal levels in the bloodstream of LH, the hormone that regulates steroid production by the interstitial cells of the testis and the ovary" [J:35782, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0001919 | abnormal reproductive system physiology | "anomaly in the function of the organs associated with producing offspring " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0001922 | reduced male fertility | "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0001925 | male infertility | "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0001926 | female infertility | "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0001940 | testicular hypoplasia | "decreased cell number in the testicles" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lamb3tm1b(KOMP)Wtsi/Lamb3tm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Lamb3tm1b(KOMP)Wtsi/H
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MP:0002188 | small heart | "reduced size of the heart relative to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:67044] |
Show
Allelic Composition: Lamb3tm1b(KOMP)Wtsi/Lamb3tm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Lamb3tm1b(KOMP)Wtsi/H
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MP:0002216 | abnormal seminiferous tubule morphology | "malformation of the tubules in the testes where spermatogenesis occurs" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0002254 | reproductive system inflammation | "local accumulation of fluid, plasma proteins, and leukocytes in any of the reproductive organs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0002286 | cryptorchism | "failure of one or both of the testes to descend into the scrotum around the time of birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0002566 | abnormal sexual interaction | "altered initiation, failure of initiation or incomplete mating behavior" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0002631 | abnormal epididymis morphology | "malformation of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0002636 | delayed vaginal opening | "the opening of the genital canal in a female occuring at a later than expected age" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0002644 | decreased circulating triglyceride level | "lower than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lamb3tm1b(KOMP)Wtsi/Lamb3tm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Lamb3tm1b(KOMP)Wtsi/H
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MP:0002660 | abnormal caput | "anomalous structure of the head of the epididymis" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0002662 | abnormal cauda | "anomalous structure of the tail of the epididymis" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0002687 | oligozoospermia | "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0002691 | small stomach | "reduced size of the stomach" [J:77398, dlb:Donna Burkart , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lamb3tm1b(KOMP)Wtsi/Lamb3tm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Lamb3tm1b(KOMP)Wtsi/H
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MP:0002773 | decreased circulating luteinizing hormone level | "lower than normal levels in the bloodstream of LH, the hormone that regulates steroid production by the interstitial cells of the testis and the ovary" [J:35132, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb,Tbx1tm6(cre)Bld/Tbx1+,Tg(Pax2-cre)1Akg/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0002774 | small prostate | "reduced size of the gland in males that secretes part of the seminiferous fluid" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0002780 | decreased circulating testosterone level | "less than the normal blood concentration of this most potent androgen" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
Allelic Composition: Lhcgrtm1Zmlei/Lhcgr+ Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0002781 | increased circulating testosterone level | "greater than the normal blood concentration of this most potent androgen" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb,Tbx1tm6(cre)Bld/Tbx1+,Tg(Pax2-cre)1Akg/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0002782 | abnormal testicular secretion | "malfunction of the production and/or release of hormones from testicular tissue" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0002783 | abnormal ovarian secretion | "malfunction of the production and/or release of hormones from ovarian tissue" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0002785 | absent Leydig cells | "lack of the interstitial cells of the seminiferous tubules that secrete testosterone " [J:65900, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
|
MP:0002790 | decreased circulating follicle stimulating hormone level | "less than expected blood concentration of the hormone that, in females, stimulates the graafian follicles of the ovary and assists in follicular maturation and the secretion of estradiol; in the male it stimulates the epithelium of the seminiferous tubules and is partly responsible for spermatogenesis " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb,Tbx1tm6(cre)Bld/Tbx1+,Tg(Pax2-cre)1Akg/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0002997 | enlarged seminal gland | "increased size, compared to the norm, of one of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens" [ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb,Tbx1tm6(cre)Bld/Tbx1+,Tg(Pax2-cre)1Akg/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0003036 | vertebral transformation | "homeotic transformation of a specific vertebrae to adopt the fate of another" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lamb3tm1b(KOMP)Wtsi/Lamb3tm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Lamb3tm1b(KOMP)Wtsi/H
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MP:0003378 | early sexual maturation | "pubertal changes occur at an earlier than normal age" [ncbi:Matthew Mailman, NCBI request] |
Show
Allelic Composition: Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb,Tbx1tm6(cre)Bld/Tbx1+,Tg(Pax2-cre)1Akg/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0003531 | abnormal vagina development | "abnormal morphogenesis of the female reproductive canal located between the uterus and the vulva" [ncbi:Matthew Mailman, NCBI request] |
Show
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0003596 | epididymal inflammation | "local accumulation of fluid, plasma proteins, and leukocytes in the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [ncbi:Matthew Mailman, NCBI request] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0003608 | prostate inflammation | "local accumulation of fluid, plasma proteins, and leukocytes in the prostate" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0003611 | scrotum hypoplasia | "reduction in size, usually due to a reduction in cell number, of the external sac of skin that encloses the testes" [ncbi:Matthew Mailman, NCBI request] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0003641 | small lung | "reduced size of the lung relative to normal" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:95332] |
Show
Allelic Composition: Lamb3tm1b(KOMP)Wtsi/Lamb3tm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Lamb3tm1b(KOMP)Wtsi/H
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MP:0003917 | increased kidney weight | "greater heft of the organs responsible for urine secretion" [RGD:Rat Genome Database submission] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0004083 | polysyndactyly | "greater than 5 digits present on an autopod with interdigital webbing also present" [rbabiuk:Randall Babiuk, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lamb3tm1b(KOMP)Wtsi/Lamb3tm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Lamb3tm1b(KOMP)Wtsi/H
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MP:0004543 | abnormal sperm physiology | "anomaly in the normal function of spermatozoa" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0004613 | fusion of vertebral arches | "improper union of the dorsal part of adjacent vertebra" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lamb3tm1b(KOMP)Wtsi/Lamb3tm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Lamb3tm1b(KOMP)Wtsi/H
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MP:0004852 | decreased testis weight | "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
Allelic Composition: Lhcgrtm1.1Pnara/Lhcgr+ Genetic Background: involves: 129S1/SvImJ * 129X1/SvJ * C57BL/6J
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MP:0004856 | decreased ovary weight | "reduction in the average weight of the female reproductive gland containing the germ cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0004909 | increased seminal gland weight | "increase in the weight of one or both of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lhcgrtm1.1Pnara/Lhcgr+ Genetic Background: involves: 129S1/SvImJ * 129X1/SvJ * C57BL/6J
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MP:0004910 | decreased seminal gland weight | "reduction in the weight of one or both of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0004928 | increased epididymis weight | "increase in the average weight of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lhcgrtm1.1Pnara/Lhcgr+ Genetic Background: involves: 129S1/SvImJ * 129X1/SvJ * C57BL/6J
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MP:0004929 | decreased epididymis weight | "reduction in the average weight of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0004930 | small epididymis | "decrease in the average size of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0004932 | epididymis hypoplasia | "underdevelopment or reduced size, usually due to a reduced number of cells, of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0004933 | abnormal epididymis epithelium morphology | "any structural anomaly of the layer of secretory cells which lines the epididymis" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0004958 | enlarged prostate | "increased size of the gland in males that secretes part of the seminiferous fluid" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lhcgrtm1.1Pnara/Lhcgr+ Genetic Background: involves: 129S1/SvImJ * 129X1/SvJ * C57BL/6J
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MP:0004961 | increased prostate weight | "greater than average weight of the gland in males that secretes part of the seminiferous fluid" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lhcgrtm1.1Pnara/Lhcgr+ Genetic Background: involves: 129S1/SvImJ * 129X1/SvJ * C57BL/6J
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MP:0005147 | prostate gland hypoplasia | "reduced size of the prostate, usually due to a reduction in cell number " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0005148 | seminal gland hypoplasia | "reduction in size, usually due to a reduction in cell number, of one of the two folded, sac shaped glands that is a diverticulum of the ductus deferens" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:64337] |
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Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0005181 | decreased circulating estradiol level | "less than the normal blood concentration of this most potent naturally occurring estrogen in mammals" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0005182 | increased circulating estradiol level | "greater than the normal blood concentration of this most potent naturally occurring estrogen in mammals" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0005185 | decreased circulating progesterone level | "less than the normal blood concentration of this antiestrogenic steroid" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:66817] |
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Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0005188 | small penis | "in comparison to the norm, reduced size of the organ of copulation and urination in the male" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:66817] |
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Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0005189 | abnormal anogenital distance | "in comparison to the norm, aberration in the measure of the length of space from the genitals to the anus" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0005536 | Leydig cell hypoplasia | "reduced numbers of the interstitial cells of the seminiferous tubules that secrete testosterone" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0008257 | thin myometrium | "reduced thickness of the smooth muscle coat of the uterus, which forms the main mass of the organ and surrounds and supports the endometrium" [MESH:A02.633.570.500, MGI:brs "Beverly Richards-Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0008258 | thin endometrium | "reduced thickness of the glandular mucous membrane lining of the uterine cavity that is hormonally responsive during the estrous/menstrual cycle and during pregnancy" [MESH:A05.360.319.679.490, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0008280 | male germ cell apoptosis | "presence of male germs cells that undergo programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0009009 | absent estrous cycle | "failure of female animals to enter or progress through their sexual cycle" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0009021 | absent estrus | "absence or failure of the estrous phase of the estrous cycle in female animals" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0009081 | thin uterus | "reduced thickness or depth of the female muscular organ of gestation" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0009088 | thin uterine horn | "reduced thickness of either one of the pair of tubular extensions from the uterine body where the uterus and the uterine tubes meet" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0009096 | decreased endometrial gland number | "fewer than normal numbers of the simple or branched tubular glands found in the mucus membrane of the uterus" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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MP:0009097 | absent endometrial glands | "absence of the simple or branched tubular uterine glands" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0009201 | external male genitalia atrophy | "wasting of the external masculine genital organs, due to injury or disease resulting in reduced size" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0009214 | vas deferens hypoplasia | "underdevelopment or reduced size of the vas deferens, usually due to a reduced number of cells" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0011385 | abnormal testosterone level | "anomaly in the concentration of a potent androgen that promotes development of male secondary sex characteristics and the development of spermatozoa and may regulate sexual desire and help maintain bone and muscle health in both males and females" [ISBN:0-683-40008-8] |
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Allelic Composition: Lhcgrtm1.1Pnara/Lhcgr+ Genetic Background: involves: 129S1/SvImJ * 129X1/SvJ * C57BL/6J
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MP:0011533 | increased urine major urinary protein level | "increased amount in the urine of a family of alpha2-microglobulin-related liver secretory proteins that comprise a major protein component of mouse urine" [MGI:csmith] |
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Allelic Composition: Lhcgrtm1.1Pnara/Lhcgr+ Genetic Background: involves: 129S1/SvImJ * 129X1/SvJ * C57BL/6J
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MP:0013307 | increased adrenal gland weight | "greater average weight of the pair of endocrine glands located above the kidney that are responsible for steroid hormone secretion from the cortex and neurotransmitter (such as epinephrine and norepinephrine) secretion from the medulla " [MGI:Anna] |
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Allelic Composition: Pkd1m1Bei/Pkd1m1Bei Genetic Background: involves: A/J * FVB/N
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MP:0013604 | abnormal adult Leydig cell differentiation | "atypical formation of or inability to produce the second or adult population of Leydig cells (ALCs) between birth and puberty; ALCs arise in the interstitium of adult testes from unknown progenitor cells and become the major source of androgens that control differentiation of the male reproductive tract and spermatogenesis; ALCs are not derived from fetal Leydig cells (FLCs), and the origin and the molecular events that control ALC differentiation are poorly understood" [PMID:23568777] |
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Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
Allelic Composition: Lhcgrtm1.1Pnara/Lhcgr+ Genetic Background: involves: 129S1/SvImJ * 129X1/SvJ * C57BL/6J
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MP:0014193 | decreased epididymal cell proliferation | "decrease in the expansion rate of any epididymal cell population by cell division" [MGI:Anna] |
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Allelic Composition: Lhcgrtm1Zmlei/Lhcgrtm1Zmlei Genetic Background: either: 129X1/SvJ-Lhcgrtm1Zmlei or (involves: 129X1/SvJ * C57BL/6)
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