ENSMUSG00000025955


Mus musculus

Features
Gene ID: ENSMUSG00000025955
  
Biological name :Akr1cl
  
Synonyms : Akr1cl / aldo-keto reductase family 1, member C-like
  
Possible biological names infered from orthology : AKR1C1 / AKR1C2 / AKR1C3 / AKR1C4 / aldo-keto reductase family 1 member C1 / aldo-keto reductase family 1 member C2 / aldo-keto reductase family 1 member C3 / aldo-keto reductase family 1 member C4 / P17516 / P42330 / P52895 / Q04828
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: C2
Gene start: 65012689
Gene end: 65032759
  
Corresponding Affymetrix probe sets: 10355176 (MoGene1.0st)   1423381_at (Mouse Genome 430 2.0 Array)   1456165_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000124333
Ensembl peptide - ENSMUSP00000063309
Ensembl peptide - ENSMUSP00000123943
NCBI entrez gene - 70861     See in Manteia.
MGI - MGI:1918111
RefSeq - NM_027582
RefSeq - NM_001310617
RefSeq Peptide - NP_001297546
RefSeq Peptide - NP_081858
swissprot - Q3UXL1
swissprot - G3XA14
swissprot - E0CYR9
Ensembl - ENSMUSG00000025955
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AKR1C1ENSG00000187134Homo sapiens
 AKR1C2ENSG00000151632Homo sapiens
 AKR1C3ENSG00000196139Homo sapiens
 AKR1C4ENSG00000198610Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Akr1c6 / P70694 / Estradiol 17 beta-dehydrogenase 5 / AKR1C1* / AKR1C2* / AKR1C3* / AKR1C4* / P17516* / P42330* / P52895* / Q04828* / aldo-keto reductase family 1 member C4* / aldo-keto re...ENSMUSG0000002121071
Q8K023 / Akr1c18 / Mus musculus aldo-keto reductase family 1, member C18 (Akr1c18), transcript variant 2, mRNA. / AKR1C1* / AKR1C2* / AKR1C3* / AKR1C4* / P17516* / P42330* / P52895* / Q0482...ENSMUSG0000002121471
Akr1c14 / aldo-keto reductase family 1, member C14 / AKR1C4* / AKR1C1* / AKR1C2* / AKR1C3* / P17516* / P42330* / P52895* / Q04828* / aldo-keto reductase family 1 member C2* / aldo-keto redu...ENSMUSG0000003371570
Akr1c20 / aldo-keto reductase family 1, member C20 / AKR1C4* / Q04828* / AKR1C2* / AKR1C3* / P17516* / P42330* / P52895* / AKR1C1* / aldo-keto reductase family 1 member C2* / aldo-keto redu...ENSMUSG0000005475769
Q91WR5 / Akr1c21 / Aldo-keto reductase family 1 member C21 / AKR1C1* / AKR1C2* / AKR1C3* / AKR1C4* / P17516* / P42330* / P52895* / Q04828* / aldo-keto reductase family 1 member C3* / aldo-...ENSMUSG0000002120768
Akr1c19 / aldo-keto reductase family 1, member C19 / AKR1C4* / AKR1C1* / AKR1C2* / AKR1C3* / P17516* / P42330* / P52895* / Q04828* / aldo-keto reductase family 1 member C2* / aldo-keto redu...ENSMUSG0000007155166
Akr1c12 / aldo-keto reductase family 1, member C12 / AKR1C4* / AKR1C1* / AKR1C2* / AKR1C3* / P17516* / P42330* / P52895* / Q04828* / aldo-keto reductase family 1 member C2* / aldo-keto redu...ENSMUSG0000002121165
Q8VC28 / Akr1c13 / Aldo-keto reductase family 1 member C13 / AKR1C1* / AKR1C2* / AKR1C3* / AKR1C4* / P17516* / P42330* / P52895* / Q04828* / aldo-keto reductase family 1 member C3* / aldo-...ENSMUSG0000002121363
Akr1d1 / Q8VCX1 / 3-oxo-5-beta-steroid 4-dehydrogenase / P51857* / aldo-keto reductase family 1 member D1*ENSMUSG0000003864154
Akr1b3 / P45376 / Aldose reductase / AKR1B1* / P15121* / aldo-keto reductase family 1 member B*ENSMUSG0000000164248
Akr1b10 / aldo-keto reductase family 1, member B10 (aldose reductase) / O60218* / C9JRZ8* / AKR1B15* / aldo-keto reductase family 1 member B10* / aldo-keto reductase family 1 member B15*ENSMUSG0000006175847
P21300 / Akr1b7 / Aldose reductase-related protein 1 / C9JRZ8* / O60218* / AKR1B10* / AKR1B15* / aldo-keto reductase family 1 member B15* / aldo-keto reductase family 1 member B10*ENSMUSG0000005213146
P45377 / Akr1b8 / Aldose reductase-related protein 2 / C9JRZ8* / O60218* / AKR1B10* / AKR1B15* / aldo-keto reductase family 1 member B15* / aldo-keto reductase family 1 member B10*ENSMUSG0000002976246
Q9DCT1 / Akr1e1 / 1,5-anhydro-D-fructose reductase / AKR1E2* / Q96JD6* / aldo-keto reductase family 1 member E2*ENSMUSG0000004541043
Akr1a1 / Q9JII6 / Alcohol dehydrogenase [NADP(+)] / P14550* / aldo-keto reductase family 1 member A1*ENSMUSG0000002869239


Protein motifs (from Interpro)
Interpro ID Name
 IPR018170  Aldo/keto reductase, conserved site
 IPR020471  Aldo/keto reductase
 IPR023210  NADP-dependent oxidoreductase domain
 IPR036812  NADP-dependent oxidoreductase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
Synthesis of bile acids and bile salts via 24-hydroxycholesterol
Synthesis of bile acids and bile salts via 27-hydroxycholesterol
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
RA biosynthesis pathway
Retinoid metabolism and transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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