Manteia

ENSMUSG00000026764

Mus musculus

Features

Gene ID:	ENSMUSG00000026764

Biological name :	Kif5c

Synonyms :	Kif5c / Kinesin heavy chain isoform 5C / P28738

Possible biological names infered from orthology :	kinesin family member 5C / O60282

Species:	Mus musculus

Chr. number:	2
Strand:	1
Band:	C1.1
Gene start:	49619298
Gene end:	49774778

Corresponding Affymetrix probe sets:	10471994 (MoGene1.0st) 1422945_a_at (Mouse Genome 430 2.0 Array) 1450804_at (Mouse Genome 430 2.0 Array) 1455266_at (Mouse Genome 430 2.0 Array) 1457255_x_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000117370 Ensembl peptide - ENSMUSP00000028102 NCBI entrez gene - 16574 See in Manteia. MGI - MGI:1098269 RefSeq - NM_008449 RefSeq Peptide - NP_032475 swissprot - A2ARD4 swissprot - P28738 Ensembl - ENSMUSG00000026764

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Kif5b / Q61768 / Kinesin-1 heavy chain / P33176* / kinesin family member 5B*	ENSMUSG00000006740	75
Kif5a / P33175 / Kinesin heavy chain isoform 5A / Q12840* / kinesin family member 5A*	ENSMUSG00000074657	74
Cenpe / centromere protein E / Q02224*	ENSMUSG00000045328	26
Kif7 / kinesin family member 7 / Q2M1P5*	ENSMUSG00000050382	25
Kif4 / P33174 / Chromosome-associated kinesin KIF4 / KIF4A* / KIF4B* / Q2VIQ3* / O95239* / kinesin family member 4B* / kinesin family member 4A*	ENSMUSG00000034311	25
Kif27 / Q7M6Z4 / Kinesin-like protein KIF27 / Q86VH2* / kinesin family member 27*	ENSMUSG00000060176	25
Kif21a / Q9QXL2 / Kinesin-like protein KIF21A / Q7Z4S6* / kinesin family member 21A*	ENSMUSG00000022629	25
Kif21b / kinesin family member 21B / O75037*	ENSMUSG00000041642	25
Kif15 / Q6P9L6 / Kinesin-like protein KIF15 / Q9NS87* / kinesin family member 15*	ENSMUSG00000036768	24
Kif17 / Q99PW8 / Kinesin-like protein KIF17 / Q9P2E2* / kinesin family member 17*	ENSMUSG00000028758	24
Kif11 / Q6P9P6 / Kinesin-like protein KIF11 / P52732* / kinesin family member 11*	ENSMUSG00000012443	24
Kif3a / P28741 / Kinesin-like protein KIF3A / Q9Y496* / kinesin family member 3A*	ENSMUSG00000018395	21
Kif3c / O35066 / Kinesin-like protein KIF3C / O14782* / kinesin family member 3C*	ENSMUSG00000020668	21
Kif3b / Q61771 / Kinesin-like protein KIF3B Kinesin-like protein KIF3B, N-terminally processed / O15066* / kinesin family member 3B*	ENSMUSG00000027475	21

Protein motifs (from Interpro)

Interpro ID	Name
IPR001752	Kinesin motor domain
IPR019821	Kinesin motor domain, conserved site
IPR027417	P-loop containing nucleoside triphosphate hydrolase
IPR027640	Kinesin-like protein
IPR036961	Kinesin motor domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0007018	microtubule-based movement	IEA
biological_process	GO:0008045	motor neuron axon guidance	IMP
biological_process	GO:0008104	protein localization	IBA
biological_process	GO:0030705	cytoskeleton-dependent intracellular transport	IBA
biological_process	GO:0051028	mRNA transport	IMP
cellular_component	GO:0005737	cytoplasm	IEA
cellular_component	GO:0005856	cytoskeleton	IEA
cellular_component	GO:0005871	kinesin complex	TAS
cellular_component	GO:0005874	microtubule	IEA
cellular_component	GO:0035253	ciliary rootlet	IDA
cellular_component	GO:0043005	neuron projection	IDA
molecular_function	GO:0000166	nucleotide binding	IEA
molecular_function	GO:0003777	microtubule motor activity	IEA
molecular_function	GO:0005515	protein binding	IPI
molecular_function	GO:0005524	ATP binding	IEA
molecular_function	GO:0008017	microtubule binding	IEA
molecular_function	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed	IBA

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0000774	reduced brain size	"smaller appearance of the brain" [J:35802]	Show Allelic Composition: Htt^tm2Detl/Htt⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
MP:0000939	reduced motor neuron number	"fewer than normal numbers of cells that innervate an effector (muscle or glandular) tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]	Show Allelic Composition: Htt^tm2Detl/Htt⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
MP:0002169	no phenotype detected	"normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Chn1^Gt714Lex/Chn1⁺,Epha4^tm1Pch/Epha4⁺ Genetic Background: involves: 129S2/SvPas * 129S5/SvEvBrd
MP:0006006	increased sensory neuron number	"greater than normal numbers of cells that innervate an effector (muscle or glandular) tissue" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Htt^tm2Detl/Htt⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
MP:0008546	abnormal vesicle-mediated transport	"anomaly in the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell" [GO:0016192]	Show Allelic Composition: Foxo3^mommeR1/Foxo3^tm1.1Rdp,Tg(HBA1-Gfp)1Ew/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/NJ

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

1 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr