ENSMUSG00000060176


Mus musculus

Features
Gene ID: ENSMUSG00000060176
  
Biological name :Kif27
  
Synonyms : Kif27 / Kinesin-like protein KIF27 / Q7M6Z4
  
Possible biological names infered from orthology : kinesin family member 27 / Q86VH2
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: B1
Gene start: 58287502
Gene end: 58359122
  
Corresponding Affymetrix probe sets: 10409666 (MoGene1.0st)   1445404_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000043304
Ensembl peptide - ENSMUSP00000153268
Ensembl peptide - ENSMUSP00000153598
NCBI entrez gene - 75050     See in Manteia.
MGI - MGI:1922300
RefSeq - XM_017315623
RefSeq - NM_175214
RefSeq - XM_017315620
RefSeq - XM_017315621
RefSeq - XM_017315622
RefSeq - XM_006517426
RefSeq - XM_006517427
RefSeq - XM_006517429
RefSeq - XM_006517431
RefSeq - XM_006517432
RefSeq - XM_006517433
RefSeq - XM_006517434
RefSeq - XM_006517435
RefSeq - XM_006517436
RefSeq - XM_006517440
RefSeq - XM_011244579
RefSeq - XM_011244580
RefSeq - XM_017315619
RefSeq Peptide - NP_780423
swissprot - Q7M6Z4
swissprot - A0A286YDI7
Ensembl - ENSMUSG00000060176
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KIF27ENSGALG00000012588Gallus gallus
 KIF27ENSG00000165115Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kif7 / kinesin family member 7 / Q2M1P5*ENSMUSG0000005038238
Kif21b / kinesin family member 21B / O75037*ENSMUSG0000004164223
Kif21a / Q9QXL2 / Kinesin-like protein KIF21A / Q7Z4S6* / kinesin family member 21A*ENSMUSG0000002262922
Kif4 / P33174 / Chromosome-associated kinesin KIF4 / KIF4A* / KIF4B* / Q2VIQ3* / O95239* / kinesin family member 4B* / kinesin family member 4A*ENSMUSG0000003431120
Cenpe / centromere protein E / Q02224*ENSMUSG0000004532819
Kif17 / Q99PW8 / Kinesin-like protein KIF17 / Q9P2E2* / kinesin family member 17*ENSMUSG0000002875818
Kif5b / Q61768 / Kinesin-1 heavy chain / P33176* / kinesin family member 5B*ENSMUSG0000000674017
Kif15 / Q6P9L6 / Kinesin-like protein KIF15 / Q9NS87* / kinesin family member 15*ENSMUSG0000003676817
Kif5c / P28738 / Kinesin heavy chain isoform 5C / O60282* / kinesin family member 5C*ENSMUSG0000002676417
Kif5a / P33175 / Kinesin heavy chain isoform 5A / Q12840* / kinesin family member 5A*ENSMUSG0000007465717
Kif3c / O35066 / Kinesin-like protein KIF3C / O14782* / kinesin family member 3C*ENSMUSG0000002066815
Kif3b / Q61771 / Kinesin-like protein KIF3B Kinesin-like protein KIF3B, N-terminally processed / O15066* / kinesin family member 3B*ENSMUSG0000002747515
Kif11 / Q6P9P6 / Kinesin-like protein KIF11 / P52732* / kinesin family member 11*ENSMUSG0000001244315
Kif3a / P28741 / Kinesin-like protein KIF3A / Q9Y496* / kinesin family member 3A*ENSMUSG0000001839515


Protein motifs (from Interpro)
Interpro ID Name
 IPR001752  Kinesin motor domain
 IPR019821  Kinesin motor domain, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR027640  Kinesin-like protein
 IPR036961  Kinesin motor domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003351 epithelial cilium movement IMP
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0021591 ventricular system development IMP
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0060271 cilium assembly IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005871 kinesin complex IBA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0008574 ATP-dependent microtubule motor activity, plus-end-directed IBA


Pathways (from Reactome)
Pathway description
COPI-dependent Golgi-to-ER retrograde traffic
Kinesins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Apoftm1(KOMP)Vlcg/Apof+
Genetic Background: involves: C57BL/6J * C57BL/6NTac

 MP:0001850 otitis media "middle ear inflammation" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60896]
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Allelic Composition: Apoftm1(KOMP)Vlcg/Apof+
Genetic Background: involves: C57BL/6J * C57BL/6NTac

 MP:0001891 hydroencephaly "excessive accumulation of cerebrospinal fluid in the brain, especially the cerebral ventricles, often leading to increased brain size and other brain trauma" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003]
Show

Allelic Composition: Apoftm1(KOMP)Vlcg/Apof+
Genetic Background: involves: C57BL/6J * C57BL/6NTac

 MP:0001917 intraventricular hemorrhage "bleeding into the brain ventricles" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Apoftm1(KOMP)Vlcg/Apof+
Genetic Background: involves: C57BL/6J * C57BL/6NTac

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Apoftm1(KOMP)Vlcg/Apof+
Genetic Background: involves: C57BL/6J * C57BL/6NTac

 MP:0002200 abnormal brain ventricle/choroid plexus morphology "malformation or absence of the brain ventricles or their associated choroid plexuses" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Apoftm1(KOMP)Vlcg/Apof+
Genetic Background: involves: C57BL/6J * C57BL/6NTac

 MP:0002236 abnormal internal nares morphology "any structural anomaly of the portion of the opening of the nasal cavity into the nasal pharynx " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Apoftm1(KOMP)Vlcg/Apof+
Genetic Background: involves: C57BL/6J * C57BL/6NTac

 MP:0010752 impaired mucociliary clearance "reduced ability to remove mucus and other foreign particles and microorganisms from the lungs by directed ciliary movement and secretory activity of the tracheobronchial submucosal glands" [MESH:E01.370.386.520, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Apoftm1(KOMP)Vlcg/Apof+
Genetic Background: involves: C57BL/6J * C57BL/6NTac

 MP:0030113 maxillary sinus inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the maxillary sinuses" [MGI:anna]
Show

Allelic Composition: Apoftm1(KOMP)Vlcg/Apof+
Genetic Background: involves: C57BL/6J * C57BL/6NTac

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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