ENSMUSG00000028546


Mus musculus

Features
Gene ID: ENSMUSG00000028546
  
Biological name :Elavl4
  
Synonyms : Elavl4 / Mus musculus ELAV like RNA binding protein 4 (Elavl4), transcript variant 5, mRNA. / Q61701
  
Possible biological names infered from orthology : ELAV like RNA binding protein 4 / P26378
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: C7
Gene start: 110203722
Gene end: 110351909
  
Corresponding Affymetrix probe sets: 10515095 (MoGene1.0st)   1428741_at (Mouse Genome 430 2.0 Array)   1450258_a_at (Mouse Genome 430 2.0 Array)   1452894_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000102207
Ensembl peptide - ENSMUSP00000099784
Ensembl peptide - ENSMUSP00000102208
Ensembl peptide - ENSMUSP00000123014
Ensembl peptide - ENSMUSP00000121828
Ensembl peptide - ENSMUSP00000120942
Ensembl peptide - ENSMUSP00000102214
Ensembl peptide - ENSMUSP00000102212
Ensembl peptide - ENSMUSP00000102210
Ensembl peptide - ENSMUSP00000099783
NCBI entrez gene - 15572     See in Manteia.
MGI - MGI:107427
RefSeq - XM_017319993
RefSeq - NM_001163399
RefSeq - NM_001347178
RefSeq - NM_010488
RefSeq - XM_006502793
RefSeq - XM_006502794
RefSeq - XM_006502795
RefSeq - XM_006502796
RefSeq - XM_006502797
RefSeq - XM_006502798
RefSeq - XM_006502799
RefSeq - XM_006502800
RefSeq - XM_006502801
RefSeq - XM_006502802
RefSeq - XM_006502803
RefSeq - XM_017319992
RefSeq - NM_001038698
RefSeq - NM_001163397
RefSeq Peptide - NP_001156871
RefSeq Peptide - NP_001334107
RefSeq Peptide - NP_034618
RefSeq Peptide - NP_001033787
RefSeq Peptide - NP_001156869
swissprot - A2A9R6
swissprot - A2A9R5
swissprot - A2A9R4
swissprot - A2A9S3
swissprot - Q61701
swissprot - Q8BVA9
swissprot - A2A9S2
swissprot - A2A9S1
swissprot - A2A9S0
swissprot - A2A9R8
Ensembl - ENSMUSG00000028546
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 elavl4ENSDARG00000045639Danio rerio
 ELAVL4ENSGALG00000010533Gallus gallus
 ELAVL4ENSG00000162374Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Elavl2 / Q60899 / Mus musculus ELAV like RNA binding protein 1 (Elavl2), transcript variant 5, mRNA. / Q12926* / ELAV like RNA binding protein 2*ENSMUSG0000000848985
Elavl3 / Q60900 / ELAV-like protein 3 / Q14576* / ELAV like RNA binding protein 3*ENSMUSG0000000341078
Elavl1 / P70372 / ELAV-like protein 1 / Q15717* / ELAV like RNA binding protein 1*ENSMUSG0000004002861
Rbms1 / Q91W59 / RNA-binding motif, single-stranded-interacting protein 1 / P29558*ENSMUSG0000002697025
Rbms3 / Q8BWL5 / RNA binding motif, single stranded interacting protein / Q6XE24* / RNA binding motif single stranded interacting protein 3*ENSMUSG0000003960724
Rbms2 / Q8VC70 / RNA-binding motif, single-stranded-interacting protein 2 / Q15434*ENSMUSG0000004004323
Puf60 / Q3UEB3 / Poly(U)-binding-splicing factor PUF60 / Q9UHX1* / poly(U) binding splicing factor 60*ENSMUSG0000000252421
P29341 / Pabpc1 / Polyadenylate-binding protein 1 ENSMUSG0000002228321
Pabpc1l / poly(A) binding protein, cytoplasmic 1-like / Q4VXU2*ENSMUSG0000005458221
Pabpc2 / P11940* / PABPC1* / poly(A) binding protein cytoplasmic 1*ENSMUSG0000005173220
Pabpc4 / poly(A) binding protein, cytoplasmic 4 / Q13310*ENSMUSG0000001125720
Pabpc6ENSMUSG0000004617320
Pabpc5 / poly(A) binding protein cytoplasmic 5 / Q96DU9*ENSMUSG0000003473213
Pabpc4l / poly(A) binding protein cytoplasmic 4 like / P0CB38*ENSMUSG0000009091913


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR002343  Paraneoplastic encephalomyelitis antigen
 IPR006548  Splicing factor ELAV/Hu
 IPR034775  Splicing factor ELAV/Hu, RNA recognition motif 1
 IPR034918  HuD, RNA recognition motif 3
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007612 learning IMP
 biological_processGO:0007626 locomotory behavior IMP
 biological_processGO:0048813 dendrite morphogenesis IMP
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003729 mRNA binding IDA
 molecular_functionGO:0017091 AU-rich element binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Myh6tm1Jse/Myh6tm1Jse
Genetic Background: involves: 129X1/SvJ * Black Swiss

 MP:0001513 limb grasping "mice clasp front and/or hind feet almost immediately upon being lifted by tail" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
Show

Allelic Composition: Myh6tm1Jse/Myh6tm1Jse
Genetic Background: involves: 129X1/SvJ * Black Swiss

 MP:0002161 abnormal fertility/fecundity "reduced ability or inability to produce live offspring" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Myh6tm1Jse/Myh6tm1Jse
Genetic Background: involves: 129X1/SvJ * Black Swiss

 MP:0003203 increased neuron apoptosis "increase in the number of neurons undergoing programmed cell death" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Myh6tm1Jse/Myh6tm1Jse
Genetic Background: involves: 129X1/SvJ * Black Swiss

 MP:0003861 abnormal nervous system development "impaired or altered growth of the components of the nervous system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Myh6tm1Jse/Myh6tm1Jse
Genetic Background: involves: 129X1/SvJ * Black Swiss

 MP:0005332 abnormal amino acid level "aberrant concentration of these organic compounds, which, when polymerized, form proteins" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Itga7tm1Burk/Itga7tm1Burk
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0009937 abnormal neuron differentiation "abnormal growth or development of the cells of the nervous system that receive, conduct, and transmit impulses" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Myh6tm1Jse/Myh6tm1Jse
Genetic Background: involves: 129X1/SvJ * Black Swiss

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Itga7tm1Burk/Itga7tm1Burk
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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