ENSMUSG00000022283


Mus musculus

Features
Gene ID: ENSMUSG00000022283
  
Biological name :Pabpc1
  
Synonyms : P29341 / Pabpc1 / Polyadenylate-binding protein 1
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: B3.1
Gene start: 36595661
Gene end: 36609668
  
Corresponding Affymetrix probe sets: 10428192 (MoGene1.0st)   1418883_a_at (Mouse Genome 430 2.0 Array)   1453840_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000001809
Ensembl peptide - ENSMUSP00000117063
Ensembl peptide - ENSMUSP00000154430
NCBI entrez gene - 18458     See in Manteia.
MGI - MGI:1349722
RefSeq - NM_008774
RefSeq - XM_011245339
RefSeq Peptide - NP_032800
swissprot - F6ZAX1
swissprot - P29341
Ensembl - ENSMUSG00000022283
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pabpc1aENSDARG00000017219Danio rerio
 pabpc1bENSDARG00000021140Danio rerio
 PABPC1ENSGALG00000030280Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pabpc6ENSMUSG0000004617381
Pabpc2 / P11940* / PABPC1* / poly(A) binding protein cytoplasmic 1*ENSMUSG0000005173280
Pabpc4 / poly(A) binding protein, cytoplasmic 4 / Q13310*ENSMUSG0000001125778
Pabpc1l / poly(A) binding protein, cytoplasmic 1-like / Q4VXU2*ENSMUSG0000005458260
Pabpc4l / poly(A) binding protein cytoplasmic 4 like / P0CB38*ENSMUSG0000009091939
Pabpc5 / poly(A) binding protein cytoplasmic 5 / Q96DU9*ENSMUSG0000003473237
Rbms1 / Q91W59 / RNA-binding motif, single-stranded-interacting protein 1 / P29558*ENSMUSG0000002697016
Rbms2 / Q8VC70 / RNA-binding motif, single-stranded-interacting protein 2 / Q15434*ENSMUSG0000004004315
Rbms3 / Q8BWL5 / RNA binding motif, single stranded interacting protein / Q6XE24* / RNA binding motif single stranded interacting protein 3*ENSMUSG0000003960715
Puf60 / Q3UEB3 / Poly(U)-binding-splicing factor PUF60 / Q9UHX1* / poly(U) binding splicing factor 60*ENSMUSG0000000252414
Elavl4 / Q61701 / Mus musculus ELAV like RNA binding protein 4 (Elavl4), transcript variant 5, mRNA. / P26378* / ELAV like RNA binding protein 4*ENSMUSG0000002854613
Elavl2 / Q60899 / Mus musculus ELAV like RNA binding protein 1 (Elavl2), transcript variant 5, mRNA. / Q12926* / ELAV like RNA binding protein 2*ENSMUSG0000000848913
Elavl1 / P70372 / ELAV-like protein 1 / Q15717* / ELAV like RNA binding protein 1*ENSMUSG0000004002812
Elavl3 / Q60900 / ELAV-like protein 3 / Q14576* / ELAV like RNA binding protein 3*ENSMUSG0000000341012


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR002004  Polyadenylate-binding protein/Hyperplastic disc protein
 IPR003954  RNA recognition motif domain, eukaryote
 IPR006515  Polyadenylate binding protein, human types 1, 2, 3, 4
 IPR035979  RNA-binding domain superfamily
 IPR036053  PABC (PABP) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0031047 gene silencing by RNA IMP
 biological_processGO:0045070 positive regulation of viral genome replication ISO
 biological_processGO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening IMP
 biological_processGO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IMP
 biological_processGO:2000623 negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay ISS
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005681 spliceosomal complex IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0010494 cytoplasmic stress granule ISS
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0036464 cytoplasmic ribonucleoprotein granule ISO
 cellular_componentGO:0071013 catalytic step 2 spliceosome ISO
 cellular_componentGO:1990124 messenger ribonucleoprotein complex IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003729 mRNA binding IEA
 molecular_functionGO:0003730 mRNA 3"-UTR binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008022 protein C-terminus binding ISO
 molecular_functionGO:0008143 poly(A) binding ISS
 molecular_functionGO:0008266 poly(U) RNA binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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