ENSMUSG00000003410


Mus musculus

Features
Gene ID: ENSMUSG00000003410
  
Biological name :Elavl3
  
Synonyms : Elavl3 / ELAV-like protein 3 / Q60900
  
Possible biological names infered from orthology : ELAV like RNA binding protein 3 / Q14576
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: A3
Gene start: 22015005
Gene end: 22052023
  
Corresponding Affymetrix probe sets: 10591706 (MoGene1.0st)   1435871_at (Mouse Genome 430 2.0 Array)   1452524_a_at (Mouse Genome 430 2.0 Array)   1455484_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000149816
Ensembl peptide - ENSMUSP00000150771
Ensembl peptide - ENSMUSP00000003501
NCBI entrez gene - 15571     See in Manteia.
MGI - MGI:109157
RefSeq - XM_006510021
RefSeq - XM_006510022
RefSeq - NM_010487
RefSeq Peptide - NP_034617
swissprot - Q60900
swissprot - A0A1L1SUG6
swissprot - A0A1L1SS95
Ensembl - ENSMUSG00000003410
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 elavl3ENSDARG00000014420Danio rerio
 ELAVL3ENSG00000196361Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Elavl4 / Q61701 / Mus musculus ELAV like RNA binding protein 4 (Elavl4), transcript variant 5, mRNA. / P26378* / ELAV like RNA binding protein 4*ENSMUSG0000002854681
Elavl2 / Q60899 / Mus musculus ELAV like RNA binding protein 1 (Elavl2), transcript variant 5, mRNA. / Q12926* / ELAV like RNA binding protein 2*ENSMUSG0000000848980
Elavl1 / P70372 / ELAV-like protein 1 / Q15717* / ELAV like RNA binding protein 1*ENSMUSG0000004002861
Rbms1 / Q91W59 / RNA-binding motif, single-stranded-interacting protein 1 / P29558*ENSMUSG0000002697026
Rbms3 / Q8BWL5 / RNA binding motif, single stranded interacting protein / Q6XE24* / RNA binding motif single stranded interacting protein 3*ENSMUSG0000003960726
Rbms2 / Q8VC70 / RNA-binding motif, single-stranded-interacting protein 2 / Q15434*ENSMUSG0000004004324
Puf60 / Q3UEB3 / Poly(U)-binding-splicing factor PUF60 / Q9UHX1* / poly(U) binding splicing factor 60*ENSMUSG0000000252423
Pabpc4 / poly(A) binding protein, cytoplasmic 4 / Q13310*ENSMUSG0000001125721
P29341 / Pabpc1 / Polyadenylate-binding protein 1 ENSMUSG0000002228321
Pabpc6ENSMUSG0000004617321
Pabpc1l / poly(A) binding protein, cytoplasmic 1-like / Q4VXU2*ENSMUSG0000005458220
Pabpc2 / P11940* / PABPC1* / poly(A) binding protein cytoplasmic 1*ENSMUSG0000005173220
Pabpc5 / poly(A) binding protein cytoplasmic 5 / Q96DU9*ENSMUSG0000003473213
Pabpc4l / poly(A) binding protein cytoplasmic 4 like / P0CB38*ENSMUSG0000009091912


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR002343  Paraneoplastic encephalomyelitis antigen
 IPR003954  RNA recognition motif domain, eukaryote
 IPR006548  Splicing factor ELAV/Hu
 IPR034775  Splicing factor ELAV/Hu, RNA recognition motif 1
 IPR034915  HuC, RNA recognition motif 3
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0030154 cell differentiation IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0017091 AU-rich element binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000948 nonconvulsive seizures "seizures without uncontrolled motor activity, but with impairment of consciousness" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Itga7tm1Burk/Itga7tm1Burk
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Itga7tm1Burk/Itga7tm1Burk
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0004994 abnormal brain wave pattern "any anomaly in the standard pattern of rhythmic and rapid fluctuation of electrical potential between parts of the brain, often visualized on an electroencephalogram (EEG); the pattern is often measured to diagnose neurological conditions such as seizure disorders (epilepsy)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Itga7tm1Burk/Itga7tm1Burk
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Elavl3tm1.1Rbd/Elavl3+
Genetic Background: either: (involves: 129 * C57BL/6) or (involves: 129 * CD-1)

 MP:0005332 abnormal amino acid level "aberrant concentration of these organic compounds, which, when polymerized, form proteins" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Itga7tm1Burk/Itga7tm1Burk
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0008840 abnormal spike wave discharge "anomaly in the characteristic epileptiformic electroencephalographic (EEG) activity detected in generalized absence epilepsy" [PMID:16725200]
Show

Allelic Composition: Itga7tm1Burk/Itga7tm1Burk
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Elavl3tm1.1Rbd/Elavl3+
Genetic Background: either: (involves: 129 * C57BL/6) or (involves: 129 * CD-1)

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Itga7tm1Burk/Itga7tm1Burk
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Itga7tm1Burk/Itga7tm1Burk
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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