ENSMUSG00000030108


Mus musculus

Features
Gene ID: ENSMUSG00000030108
  
Biological name :Slc6a13
  
Synonyms : P31649 / Slc6a13 / Sodium- and chloride-dependent GABA transporter 2
  
Possible biological names infered from orthology : Q9NSD5 / solute carrier family 6 member 13
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: F1
Gene start: 121300227
Gene end: 121337733
  
Corresponding Affymetrix probe sets: 10541318 (MoGene1.0st)   1424338_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000066779
Ensembl peptide - ENSMUSP00000120689
NCBI entrez gene - 14412     See in Manteia.
MGI - MGI:95629
RefSeq - XM_006505538
RefSeq - NM_144512
RefSeq - XM_006505537
RefSeq Peptide - NP_653095
swissprot - P31649
swissprot - D3YWZ5
Ensembl - ENSMUSG00000030108
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SLC6A13ENSDARG00000067567Danio rerio
 SLC6A13ENSGALG00000012985Gallus gallus
 Q9NSD5ENSG00000010379Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P31650 / Slc6a11 / Sodium- and chloride-dependent GABA transporter 3 / P48066* / solute carrier family 6 member 11*ENSMUSG0000003030768
Slc6a12 / solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 / P48065* / solute carrier family 6 member 12*ENSMUSG0000003010967
O35316 / Slc6a6 / solute carrier family 6 (neurotransmitter transporter, taurine), member 6 / P31641* / solute carrier family 6 member 6*ENSMUSG0000003009662
Q8VBW1 / Slc6a8 / solute carrier family 6 (neurotransmitter transporter, creatine), member 8 / P48029* / solute carrier family 6 member 8*ENSMUSG0000001955854
P31648 / Slc6a1 / Sodium- and chloride-dependent GABA transporter 1 / P30531* / solute carrier family 6 member 1*ENSMUSG0000003031050
Q6PGE7 / Slc6a7 / Sodium-dependent proline transporter / Q99884* / solute carrier family 6 member 7*ENSMUSG0000005202645
Slc6a5 / solute carrier family 6 (neurotransmitter transporter, glycine), member 5 / Q9Y345* / solute carrier family 6 member 5*ENSMUSG0000003972844
O55192 / Slc6a2 / solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 / P23975* / solute carrier family 6 member 2*ENSMUSG0000005536843
P28571 / Slc6a9 / Sodium- and chloride-dependent glycine transporter 1 / P48067* / solute carrier family 6 member 9*ENSMUSG0000002854242
Q9JMA9 / Slc6a14 / Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) / Q9UN76* / solute carrier family 6 member 14*ENSMUSG0000003108941
Q60857 / Slc6a4 / Sodium-dependent serotonin transporter / P31645* / solute carrier family 6 member 4*ENSMUSG0000002083841
Q61327 / Slc6a3 / Sodium-dependent dopamine transporter / Q01959* / solute carrier family 6 member 3*ENSMUSG0000002160941


Protein motifs (from Interpro)
Interpro ID Name
 IPR000175  Sodium:neurotransmitter symporter
 IPR002981  Sodium:neurotransmitter symporter, GABA, GAT-2
 IPR037272  Sodium:neurotransmitter symporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006836 neurotransmitter transport IEA
 biological_processGO:0015812 gamma-aminobutyric acid transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005215 transporter activity IBA
 molecular_functionGO:0005328 neurotransmitter:sodium symporter activity IEA
 molecular_functionGO:0005332 gamma-aminobutyric acid:sodium symporter activity IEA
 molecular_functionGO:0015293 symporter activity IEA


Pathways (from Reactome)
Pathway description
Na+/Cl- dependent neurotransmitter transporters
Reuptake of GABA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005332 abnormal amino acid level "aberrant concentration of these organic compounds, which, when polymerized, form proteins" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Sp7tm1Rnis/Sp7tm1Rnis,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: C57BL * C57BL/6 * CBA/JNCrlj * SJL/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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