ENSMUSG00000041287


Mus musculus

Features
Gene ID: ENSMUSG00000041287
  
Biological name :Sox15
  
Synonyms : P43267 / Sox15 / SRY (sex determining region Y)-box 15
  
Possible biological names infered from orthology : O60248 / SRY-box 15
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B3
Gene start: 69655314
Gene end: 69656727
  
Corresponding Affymetrix probe sets: 10377588 (MoGene1.0st)   1452017_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000048524
NCBI entrez gene - 20670     See in Manteia.
MGI - MGI:98363
RefSeq - NM_009235
RefSeq Peptide - NP_033261
swissprot - P43267
swissprot - Q5F2B2
Ensembl - ENSMUSG00000041287
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SOX15ENSG00000129194Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Sox3 / SRY-box 3 / P41225*ENSMUSG0000004517944
Sox1 / P53783 / Transcription factor SOX-1 / O00570* / SRY-box 1*ENSMUSG0000009601440
Sox2 / SRY-box 2 / P48431*ENSMUSG0000007463740
Sox14 / Q04892 / Transcription factor SOX-14 / O95416* / SRY-box 14*ENSMUSG0000005374735
Sox21 / Q811W0 / Transcription factor SOX-21 / Q9Y651* / SRY-box 21*ENSMUSG0000006151734
Sox4 / Q06831 / Transcription factor SOX-4 / Q06945* / SRY-box 4*ENSMUSG0000007643131
Sox9 / Q04887 / Transcription factor SOX-9 / P48436* / SRY-box 9*ENSMUSG0000000056731
Sox17 / Q61473 / Transcription factor SOX-17 / Q9H6I2* / SRY-box 17*ENSMUSG0000002590231
Sox7 / P40646 / SRY (sex determining region Y)-box 7 / Q9BT81* / SRY-box 7*ENSMUSG0000006306031
Sox10 / Q04888 / Transcription factor SOX-10 / P56693* / SRY-box 10*ENSMUSG0000003300630
Sox8 / Q04886 / SRY (sex determining region Y)-box 8 / P57073* / SRY-box 8*ENSMUSG0000002417630
Sox18 / P43680 / Transcription factor SOX-18 / P35713* / SRY-box 18*ENSMUSG0000004647030
Sox11 / Q7M6Y2 / Transcription factor SOX-11 / P35716* / SRY-box 11*ENSMUSG0000006363228
Sox12 / Q04890 / Transcription factor SOX-12 / O15370* / SRY-box 12*ENSMUSG0000005181728
Sry / Q05738 / sex determining region of Chr Y / Q05066* / sex determining region Y*ENSMUSG0000006903624


Protein motifs (from Interpro)
Interpro ID Name
 IPR009071  High mobility group box domain
 IPR031269  Protein SOX-15
 IPR036910  High mobility group box domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IMP
 biological_processGO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration IMP
 biological_processGO:0030154 cell differentiation IGI
 biological_processGO:0043403 skeletal muscle tissue regeneration IMP
 biological_processGO:0045843 negative regulation of striated muscle tissue development IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IGI
 biological_processGO:0048627 myoblast development IMP
 biological_processGO:0070318 positive regulation of G0 to G1 transition IMP
 biological_processGO:2000288 positive regulation of myoblast proliferation IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0044798 nuclear transcription factor complex IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IGI
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046982 protein heterodimerization activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000729 abnormal myogenesis "anomaly in embryonic formation of muscle cells or fibers" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Timp3tm1Rkho/Timp3tm1Rkho
Genetic Background: B6.129-Timp3tm1Rkho

 MP:0000730 increased number of satellite cells "greater number of unfused cells in muscle that play a role in muscle regeneration" [J:42574]
Show

Allelic Composition: Timp3tm1Rkho/Timp3tm1Rkho
Genetic Background: B6.129-Timp3tm1Rkho

 MP:0000750 abnormal muscle regeneration "inability or defects in ability to repair muscle after injuries" [J:42574]
Show

Allelic Composition: Timp3tm1Rkho/Timp3tm1Rkho
Genetic Background: B6.129-Timp3tm1Rkho

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Chgatm1Skmt/Chga+
Genetic Background: involves: 129S1/Sv * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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