ENSMUSG00000044359


Mus musculus

Features
Gene ID: ENSMUSG00000044359
  
Biological name :P2ry4
  
Synonyms : P2ry4 / P2Y purinoceptor 4 / Q9JJS7
  
Possible biological names infered from orthology : P51582 / pyrimidinergic receptor P2Y4
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: C3
Gene start: 100590154
Gene end: 100594869
  
Corresponding Affymetrix probe sets: 10605938 (MoGene1.0st)   1422276_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000055869
NCBI entrez gene - 57385     See in Manteia.
MGI - MGI:1926594
RefSeq - XM_006528178
RefSeq - NM_020621
RefSeq - XM_006528175
RefSeq - XM_006528176
RefSeq - XM_006528177
RefSeq Peptide - NP_065646
swissprot - Q0VBT7
swissprot - Q9JJS7
Ensembl - ENSMUSG00000044359
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P2RY4ENSGALG00000004346Gallus gallus
 P2RY4ENSG00000186912Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P2ry2 / purinergic receptor P2Y2 / P41231*ENSMUSG0000003286050
P2ry1 / P49650 / purinergic receptor P2Y, G-protein coupled 1 / P47900* / purinergic receptor P2Y1*ENSMUSG0000002776536
P2ry6 / Q9ERK9 / P2Y purinoceptor 6 / Q15077* / pyrimidinergic receptor P2Y6*ENSMUSG0000004877935
Lpar5 / lysophosphatidic acid receptor 5 / Q9H1C0*ENSMUSG0000006771429
Gpr17 / Q6NS65 / Uracil nucleotide/cysteinyl leukotriene receptor / Q13304* / G protein-coupled receptor 17*ENSMUSG0000005222929
Lpar6 / Q8BMC0 / Lysophosphatidic acid receptor 6 / P43657*ENSMUSG0000003344628
Oxgr1 / Q6IYF8 / 2-oxoglutarate receptor 1 / Q96P68* / oxoglutarate receptor 1*ENSMUSG0000004481927
Lpar4 / Q8BLG2 / Lysophosphatidic acid receptor 4 / Q99677*ENSMUSG0000004992927
Gpr174 / Q3U507 / G protein-coupled receptor 174 / Q9BXC1*ENSMUSG0000007300825
Gpr183 / Q3U6B2 / G protein-coupled receptor 183 / P32249*ENSMUSG0000005121224
P2ry10 / Q8BFU7 / Mus musculus purinergic receptor P2Y, G-protein coupled 10 (P2ry10), transcript variant 2, mRNA. / O00398* / P2Y receptor family member 10*ENSMUSG0000005092123
Q99MT6 / Sucnr1 / Succinate receptor 1 / Q9BXA5*ENSMUSG0000002776223
Q99JA4 / Cysltr1 / Cysteinyl leukotriene receptor 1 / Q9Y271*ENSMUSG0000005282123
Ptafr / Q62035 / Platelet-activating factor receptor / P25105*ENSMUSG0000005652922
P2ry10b / purinergic receptor P2Y, G-protein coupled 10BENSMUSG0000005429322
Q920A1 / Cysltr2 / Cysteinyl leukotriene receptor 2 / Q9NS75*ENSMUSG0000003347021


Protein motifs (from Interpro)
Interpro ID Name
 IPR000018  P2Y purinoceptor 4
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0030321 transepithelial chloride transport IDA
 biological_processGO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway IEA
 biological_processGO:0071380 cellular response to prostaglandin E stimulus IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0019103 pyrimidine nucleotide binding IC
 molecular_functionGO:0045028 G-protein coupled purinergic nucleotide receptor activity IEA
 molecular_functionGO:0045030 UTP-activated nucleotide receptor activity IDA


Pathways (from Reactome)
Pathway description
P2Y receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000501 abnormal digestive secretion "malfunction of the production and/or release of a physiologically active substance (usually but not exclusively in liquid form) from a cell or a gland of the digestive system" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:tc]
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Allelic Composition: Ihhtm1Blan/Ihhtm1Blan,Tg(Col2a1-cre)10Amc/0
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: P2ry4tm1Brob/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0011090 partial perinatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
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Allelic Composition: Ihhtm1Blan/Ihhtm1Blan,Tg(Col2a1-cre)10Amc/0
Genetic Background: involves: 129S4/SvJae * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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