ENSG00000186912


Homo sapiens

Features
Gene ID: ENSG00000186912
  
Biological name :P2RY4
  
Synonyms : P2RY4 / P51582 / pyrimidinergic receptor P2Y4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: q13.1
Gene start: 70258170
Gene end: 70259764
  
Corresponding Affymetrix probe sets: 221466_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000363643
NCBI entrez gene - 5030     See in Manteia.
OMIM - 300038
RefSeq - NM_002565
RefSeq Peptide - NP_002556
swissprot - P51582
Ensembl - ENSG00000186912
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P2RY4ENSGALG00000004346Gallus gallus
 P2ry4ENSMUSG00000044359Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P2RY2 / P41231 / purinergic receptor P2Y2ENSG0000017559152
P2RY1 / P47900 / purinergic receptor P2Y1ENSG0000016986037
P2RY6 / Q15077 / pyrimidinergic receptor P2Y6ENSG0000017163135
GPR17 / Q13304 / G protein-coupled receptor 17ENSG0000014423029
LPAR5 / Q9H1C0 / lysophosphatidic acid receptor 5ENSG0000018457428
P2RY11 / Q96G91 / purinergic receptor P2Y11ENSG0000024416528
PPAN-P2RY11 / PPAN-P2RY11 readthroughENSG0000024320728
OXGR1 / Q96P68 / oxoglutarate receptor 1ENSG0000016562127
LPAR6 / P43657 / lysophosphatidic acid receptor 6ENSG0000013967927
LPAR4 / Q99677 / lysophosphatidic acid receptor 4ENSG0000014714526
Q9BXA5 / SUCNR1 / succinate receptor 1ENSG0000019882925
O00398 / P2RY10 / P2Y receptor family member 10ENSG0000007858924
GPR174 / Q9BXC1 / G protein-coupled receptor 174ENSG0000014713824
GPR183 / P32249 / G protein-coupled receptor 183ENSG0000016950824
PTAFR / P25105 / platelet activating factor receptorENSG0000016940323
Q9NS75 / CYSLTR2 / cysteinyl leukotriene receptor 2ENSG0000015220722
Q9Y271 / CYSLTR1 / cysteinyl leukotriene receptor 1ENSG0000017319822


Protein motifs (from Interpro)
Interpro ID Name
 IPR000018  P2Y purinoceptor 4
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration TAS
 biological_processGO:0030321 transepithelial chloride transport IEA
 biological_processGO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway IEA
 biological_processGO:0071380 cellular response to prostaglandin E stimulus IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0015065 uridine nucleotide receptor activity TAS
 molecular_functionGO:0045028 G-protein coupled purinergic nucleotide receptor activity IEA
 molecular_functionGO:0045030 UTP-activated nucleotide receptor activity IEA


Pathways (from Reactome)
Pathway description
P2Y receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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