ENSG00000147145


Homo sapiens

Features
Gene ID: ENSG00000147145
  
Biological name :LPAR4
  
Synonyms : LPAR4 / lysophosphatidic acid receptor 4 / Q99677
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: q21.1
Gene start: 78747709
Gene end: 78757094
  
Corresponding Affymetrix probe sets: 206960_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000408205
Ensembl peptide - ENSP00000476460
Ensembl peptide - ENSP00000478261
NCBI entrez gene - 2846     See in Manteia.
OMIM - 300086
RefSeq - XM_017029438
RefSeq - NM_001278000
RefSeq - NM_005296
RefSeq - XM_005262126
RefSeq - XM_006724639
RefSeq - XM_017029437
RefSeq Peptide - NP_001264929
RefSeq Peptide - NP_005287
swissprot - Q99677
swissprot - V9GY74
Ensembl - ENSG00000147145
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lpar4ENSDARG00000089824Danio rerio
 LPAR4ENSGALG00000004121Gallus gallus
 Lpar4ENSMUSG00000049929Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LPAR6 / P43657 / lysophosphatidic acid receptor 6ENSG0000013967949
LPAR5 / Q9H1C0 / lysophosphatidic acid receptor 5ENSG0000018457429
GPR174 / Q9BXC1 / G protein-coupled receptor 174ENSG0000014713828
O00398 / P2RY10 / P2Y receptor family member 10ENSG0000007858927
PTAFR / P25105 / platelet activating factor receptorENSG0000016940326
GPR17 / Q13304 / G protein-coupled receptor 17ENSG0000014423026
P2RY2 / P41231 / purinergic receptor P2Y2ENSG0000017559126
Q9NS75 / CYSLTR2 / cysteinyl leukotriene receptor 2ENSG0000015220726
P2RY4 / P51582 / pyrimidinergic receptor P2Y4ENSG0000018691226
Q9Y271 / CYSLTR1 / cysteinyl leukotriene receptor 1ENSG0000017319825
GPR183 / P32249 / G protein-coupled receptor 183ENSG0000016950825
P2RY1 / P47900 / purinergic receptor P2Y1ENSG0000016986025
P2RY6 / Q15077 / pyrimidinergic receptor P2Y6ENSG0000017163124
OXGR1 / Q96P68 / oxoglutarate receptor 1ENSG0000016562123
PPAN-P2RY11 / PPAN-P2RY11 readthroughENSG0000024320721
Q9BXA5 / SUCNR1 / succinate receptor 1ENSG0000019882921
P2RY11 / Q96G91 / purinergic receptor P2Y11ENSG0000024416520


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0035025 positive regulation of Rho protein signal transduction IBA
 biological_processGO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway IBA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016604 nuclear body IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0035727 lysophosphatidic acid binding IEA
 molecular_functionGO:0070915 lysophosphatidic acid receptor activity IBA


Pathways (from Reactome)
Pathway description
G alpha (q) signalling events
P2Y receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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