ENSG00000169508


Homo sapiens

Features
Gene ID: ENSG00000169508
  
Biological name :GPR183
  
Synonyms : GPR183 / G protein-coupled receptor 183 / P32249
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: -1
Band: q32.3
Gene start: 99294530
Gene end: 99307405
  
Corresponding Affymetrix probe sets: 205419_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000365596
NCBI entrez gene - 1880     See in Manteia.
OMIM - 605741
RefSeq - XM_017020405
RefSeq - NM_004951
RefSeq Peptide - NP_004942
swissprot - P32249
swissprot - A0A024RDX2
Ensembl - ENSG00000169508
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 B0UXR0ENSDARG00000074302Danio rerio
 gpr183aENSDARG00000010317Danio rerio
 GPR183ENSGALG00000016881Gallus gallus
 Gpr183ENSMUSG00000051212Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9NS75 / CYSLTR2 / cysteinyl leukotriene receptor 2ENSG0000015220727
LPAR4 / Q99677 / lysophosphatidic acid receptor 4ENSG0000014714525
P2RY2 / P41231 / purinergic receptor P2Y2ENSG0000017559124
P2RY1 / P47900 / purinergic receptor P2Y1ENSG0000016986024
GPR174 / Q9BXC1 / G protein-coupled receptor 174ENSG0000014713824
LPAR6 / P43657 / lysophosphatidic acid receptor 6ENSG0000013967924
P2RY4 / P51582 / pyrimidinergic receptor P2Y4ENSG0000018691224
LPAR5 / Q9H1C0 / lysophosphatidic acid receptor 5ENSG0000018457424
Q9Y271 / CYSLTR1 / cysteinyl leukotriene receptor 1ENSG0000017319824
GPR17 / Q13304 / G protein-coupled receptor 17ENSG0000014423024
O00398 / P2RY10 / P2Y receptor family member 10ENSG0000007858923
Q9BXA5 / SUCNR1 / succinate receptor 1ENSG0000019882922
P2RY6 / Q15077 / pyrimidinergic receptor P2Y6ENSG0000017163122
PTAFR / P25105 / platelet activating factor receptorENSG0000016940322
OXGR1 / Q96P68 / oxoglutarate receptor 1ENSG0000016562121
P2RY11 / Q96G91 / purinergic receptor P2Y11ENSG0000024416519
PPAN-P2RY11 / PPAN-P2RY11 readthroughENSG0000024320719


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response ISS
 biological_processGO:0002312 B cell activation involved in immune response IBA
 biological_processGO:0002313 mature B cell differentiation involved in immune response ISS
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002407 dendritic cell chemotaxis ISS
 biological_processGO:0006955 immune response TAS
 biological_processGO:0006959 humoral immune response ISS
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0010818 T cell chemotaxis ISS
 biological_processGO:0030316 osteoclast differentiation ISS
 biological_processGO:0030595 leukocyte chemotaxis IMP
 biological_processGO:0030890 positive regulation of B cell proliferation IDA
 biological_processGO:0036145 dendritic cell homeostasis ISS
 biological_processGO:0060326 cell chemotaxis IEA
 biological_processGO:0061470 T follicular helper cell differentiation ISS
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IDA
 biological_processGO:2000458 regulation of astrocyte chemotaxis IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity TAS
 molecular_functionGO:0008142 oxysterol binding IMP


Pathways (from Reactome)
Pathway description
Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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