ENSG00000173198


Homo sapiens

Features
Gene ID: ENSG00000173198
  
Biological name :CYSLTR1
  
Synonyms : CYSLTR1 / cysteinyl leukotriene receptor 1 / Q9Y271
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: q21.1
Gene start: 78271464
Gene end: 78327691
  
Corresponding Affymetrix probe sets: 216288_at (Human Genome U133 Plus 2.0 Array)   230866_at (Human Genome U133 Plus 2.0 Array)   231747_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000362401
Ensembl peptide - ENSP00000478492
NCBI entrez gene - 10800     See in Manteia.
OMIM - 300201
RefSeq - NM_001282188
RefSeq - NM_001282186
RefSeq - NM_001282187
RefSeq - NM_006639
RefSeq Peptide - NP_001269115
RefSeq Peptide - NP_001269116
RefSeq Peptide - NP_001269117
RefSeq Peptide - NP_006630
swissprot - Q9Y271
Ensembl - ENSG00000173198
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cysltr1ENSDARG00000058246Danio rerio
 CYSLTR1ENSGALG00000004128Gallus gallus
 Q99JA4ENSMUSG00000052821Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9NS75 / CYSLTR2 / cysteinyl leukotriene receptor 2ENSG0000015220734
LPAR6 / P43657 / lysophosphatidic acid receptor 6ENSG0000013967929
P2RY1 / P47900 / purinergic receptor P2Y1ENSG0000016986028
GPR17 / Q13304 / G protein-coupled receptor 17ENSG0000014423028
LPAR4 / Q99677 / lysophosphatidic acid receptor 4ENSG0000014714528
O00398 / P2RY10 / P2Y receptor family member 10ENSG0000007858926
GPR174 / Q9BXC1 / G protein-coupled receptor 174ENSG0000014713826
OXGR1 / Q96P68 / oxoglutarate receptor 1ENSG0000016562126
GPR183 / P32249 / G protein-coupled receptor 183ENSG0000016950826
Q9BXA5 / SUCNR1 / succinate receptor 1ENSG0000019882926
P2RY2 / P41231 / purinergic receptor P2Y2ENSG0000017559126
P2RY6 / Q15077 / pyrimidinergic receptor P2Y6ENSG0000017163125
PTAFR / P25105 / platelet activating factor receptorENSG0000016940324
P2RY4 / P51582 / pyrimidinergic receptor P2Y4ENSG0000018691224
LPAR5 / Q9H1C0 / lysophosphatidic acid receptor 5ENSG0000018457423
P2RY11 / Q96G91 / purinergic receptor P2Y11ENSG0000024416521
PPAN-P2RY11 / PPAN-P2RY11 readthroughENSG0000024320720


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR004071  Cysteinyl leukotriene receptor
 IPR013310  Cysteinyl leukotriene receptor 1
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002437 inflammatory response to antigenic stimulus IEA
 biological_processGO:0003013 circulatory system process IBA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0006952 defense response TAS
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway IBA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration TAS
 biological_processGO:0007218 neuropeptide signaling pathway IBA
 biological_processGO:0007585 respiratory gaseous exchange TAS
 biological_processGO:0061737 leukotriene signaling pathway IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004974 leukotriene receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008528 G-protein coupled peptide receptor activity IBA


Pathways (from Reactome)
Pathway description
Leukotriene receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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