ENSG00000175591


Homo sapiens

Features
Gene ID: ENSG00000175591
  
Biological name :P2RY2
  
Synonyms : P2RY2 / P41231 / purinergic receptor P2Y2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q13.4
Gene start: 73218298
Gene end: 73236352
  
Corresponding Affymetrix probe sets: 206277_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000310305
Ensembl peptide - ENSP00000377221
Ensembl peptide - ENSP00000377222
NCBI entrez gene - 5029     See in Manteia.
OMIM - 600041
RefSeq - XM_017017839
RefSeq - NM_002564
RefSeq - NM_176071
RefSeq - NM_176072
RefSeq - XM_005274019
RefSeq - XM_005274020
RefSeq - XM_005274021
RefSeq - XM_011545074
RefSeq Peptide - NP_788085
RefSeq Peptide - NP_788086
RefSeq Peptide - NP_002555
swissprot - P41231
Ensembl - ENSG00000175591
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 p2ry2.1ENSDARG00000099915Danio rerio
 p2ry2.2ENSDARG00000104927Danio rerio
 p2ry2.3ENSDARG00000104425Danio rerio
 P2RY2ENSGALG00000042317Gallus gallus
 P2ry2ENSMUSG00000032860Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P2RY4 / P51582 / pyrimidinergic receptor P2Y4ENSG0000018691250
P2RY1 / P47900 / purinergic receptor P2Y1ENSG0000016986033
P2RY6 / Q15077 / pyrimidinergic receptor P2Y6ENSG0000017163133
LPAR5 / Q9H1C0 / lysophosphatidic acid receptor 5ENSG0000018457426
GPR174 / Q9BXC1 / G protein-coupled receptor 174ENSG0000014713825
OXGR1 / Q96P68 / oxoglutarate receptor 1ENSG0000016562125
LPAR4 / Q99677 / lysophosphatidic acid receptor 4ENSG0000014714525
Q9BXA5 / SUCNR1 / succinate receptor 1ENSG0000019882925
LPAR6 / P43657 / lysophosphatidic acid receptor 6ENSG0000013967925
GPR17 / Q13304 / G protein-coupled receptor 17ENSG0000014423025
PTAFR / P25105 / platelet activating factor receptorENSG0000016940324
O00398 / P2RY10 / P2Y receptor family member 10ENSG0000007858924
Q9NS75 / CYSLTR2 / cysteinyl leukotriene receptor 2ENSG0000015220724
PPAN-P2RY11 / PPAN-P2RY11 readthroughENSG0000024320724
P2RY11 / Q96G91 / purinergic receptor P2Y11ENSG0000024416524
GPR183 / P32249 / G protein-coupled receptor 183ENSG0000016950823
Q9Y271 / CYSLTR1 / cysteinyl leukotriene receptor 1ENSG0000017319823


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000356  P2Y2 purinoceptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006873 cellular ion homeostasis TAS
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway TAS
 biological_processGO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway IEA
 biological_processGO:0070257 positive regulation of mucus secretion IEA
 biological_processGO:0097746 regulation of blood vessel diameter IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0045028 G-protein coupled purinergic nucleotide receptor activity IEA


Pathways (from Reactome)
Pathway description
G alpha (q) signalling events
P2Y receptors
Surfactant metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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