ENSG00000171631


Homo sapiens

Features
Gene ID: ENSG00000171631
  
Biological name :P2RY6
  
Synonyms : P2RY6 / pyrimidinergic receptor P2Y6 / Q15077
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q13.4
Gene start: 73264505
Gene end: 73298617
  
Corresponding Affymetrix probe sets: 208373_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000445652
Ensembl peptide - ENSP00000443427
Ensembl peptide - ENSP00000480966
Ensembl peptide - ENSP00000309771
Ensembl peptide - ENSP00000377215
Ensembl peptide - ENSP00000377216
Ensembl peptide - ENSP00000377217
Ensembl peptide - ENSP00000440770
Ensembl peptide - ENSP00000441079
Ensembl peptide - ENSP00000442509
Ensembl peptide - ENSP00000442551
Ensembl peptide - ENSP00000442990
NCBI entrez gene - 5031     See in Manteia.
OMIM - 602451
RefSeq - XM_011545079
RefSeq - NM_001277204
RefSeq - NM_001277205
RefSeq - NM_001277206
RefSeq - NM_001277207
RefSeq - NM_001277208
RefSeq - NM_176796
RefSeq - NM_176797
RefSeq - NM_176798
RefSeq - XM_005274022
RefSeq - XM_006718571
RefSeq - XM_011545077
RefSeq Peptide - NP_001264133
RefSeq Peptide - NP_001264134
RefSeq Peptide - NP_001264136
RefSeq Peptide - NP_001264137
RefSeq Peptide - NP_789766
RefSeq Peptide - NP_789767
RefSeq Peptide - NP_789768
RefSeq Peptide - NP_001264135
swissprot - F5GX90
swissprot - F5GYF3
swissprot - F5H7H9
swissprot - Q15077
swissprot - A0A024R5I9
Ensembl - ENSG00000171631
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-6n21.13ENSDARG00000069459Danio rerio
 P2RY6ENSGALG00000017327Gallus gallus
 P2ry6ENSMUSG00000048779Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P2RY2 / P41231 / purinergic receptor P2Y2ENSG0000017559138
P2RY4 / P51582 / pyrimidinergic receptor P2Y4ENSG0000018691238
P2RY1 / P47900 / purinergic receptor P2Y1ENSG0000016986033
LPAR5 / Q9H1C0 / lysophosphatidic acid receptor 5ENSG0000018457429
OXGR1 / Q96P68 / oxoglutarate receptor 1ENSG0000016562129
GPR17 / Q13304 / G protein-coupled receptor 17ENSG0000014423028
LPAR4 / Q99677 / lysophosphatidic acid receptor 4ENSG0000014714527
Q9BXA5 / SUCNR1 / succinate receptor 1ENSG0000019882927
LPAR6 / P43657 / lysophosphatidic acid receptor 6ENSG0000013967927
Q9NS75 / CYSLTR2 / cysteinyl leukotriene receptor 2ENSG0000015220726
Q9Y271 / CYSLTR1 / cysteinyl leukotriene receptor 1ENSG0000017319826
O00398 / P2RY10 / P2Y receptor family member 10ENSG0000007858926
PPAN-P2RY11 / PPAN-P2RY11 readthroughENSG0000024320725
GPR174 / Q9BXC1 / G protein-coupled receptor 174ENSG0000014713825
P2RY11 / Q96G91 / purinergic receptor P2Y11ENSG0000024416524
GPR183 / P32249 / G protein-coupled receptor 183ENSG0000016950824
PTAFR / P25105 / platelet activating factor receptorENSG0000016940321


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR001973  P2Y6 purinoceptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway TAS
 biological_processGO:0014911 positive regulation of smooth muscle cell migration IEA
 biological_processGO:0030321 transepithelial chloride transport IEA
 biological_processGO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway IEA
 biological_processGO:0071380 cellular response to prostaglandin E stimulus IEA
 biological_processGO:0071407 cellular response to organic cyclic compound IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0045028 G-protein coupled purinergic nucleotide receptor activity IEA
 molecular_functionGO:0045029 UDP-activated nucleotide receptor activity IEA


Pathways (from Reactome)
Pathway description
G alpha (q) signalling events
P2Y receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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