ENSMUSG00000050783


Mus musculus

Features
Gene ID: ENSMUSG00000050783
  
Biological name :Htr1f
  
Synonyms : 5-hydroxytryptamine (serotonin) receptor 1F / Htr1f / Q02284
  
Possible biological names infered from orthology : 5-hydroxytryptamine receptor 1F / P30939
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: C1.3
Gene start: 64924729
Gene end: 65105784
  
Corresponding Affymetrix probe sets: 10440302 (MoGene1.0st)   1440422_at (Mouse Genome 430 2.0 Array)   1450548_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000063136
NCBI entrez gene - 15557     See in Manteia.
MGI - MGI:99842
RefSeq - NM_008310
RefSeq Peptide - NP_032336
swissprot - Q02284
swissprot - Q543V2
Ensembl - ENSMUSG00000050783
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 htr1faENSDARG00000109862Danio rerio
 htr1fbENSDARG00000053580Danio rerio
 HTR1FENSGALG00000015494Gallus gallus
 HTR1FENSG00000179097Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Htr1d / Q61224 / 5-hydroxytryptamine (serotonin) receptor 1D / P28221* / 5-hydroxytryptamine receptor 1D*ENSMUSG0000007068747
Htr1b / P28334 / 5-hydroxytryptamine (serotonin) receptor 1B / P28222* / 5-hydroxytryptamine receptor 1B*ENSMUSG0000004951145
Htr1a / Q64264 / 5-hydroxytryptamine (serotonin) receptor 1A / P08908* / 5-hydroxytryptamine receptor 1A*ENSMUSG0000002172142
Htr7 / P32304 / 5-hydroxytryptamine (serotonin) receptor 7 / P34969* / 5-hydroxytryptamine receptor 7*ENSMUSG0000002479835
Adra2a / adrenoceptor alpha 2A / P08913*ENSMUSG0000003371734
Htr5a / P30966 / 5-hydroxytryptamine (serotonin) receptor 5A / P47898* / 5-hydroxytryptamine receptor 5A*ENSMUSG0000003910634
Htr5b / 5-hydroxytryptamine (serotonin) receptor 5BENSMUSG0000005053432
Adra1b / adrenoceptor alpha 1B / P35368*ENSMUSG0000005054132
Adra1a / P97718 / Alpha-1A adrenergic receptor / P35348* / adrenoceptor alpha 1A*ENSMUSG0000004587532
Adra2c / Q01337 / Alpha-2C adrenergic receptor / P18825* / adrenoceptor alpha 2C*ENSMUSG0000004531831
Adra2b / adrenoceptor alpha 2B / P18089*ENSMUSG0000005862030
Adra1d / adrenoceptor alpha 1D / P25100*ENSMUSG0000002733528


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000450  5-Hydroxytryptamine 1F receptor
 IPR002231  5-hydroxytryptamine receptor family
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway IEA
 biological_processGO:0098664 G-protein coupled serotonin receptor signaling pathway IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004993 G-protein coupled serotonin receptor activity ISS
 molecular_functionGO:0030594 neurotransmitter receptor activity IBA
 molecular_functionGO:0051378 serotonin binding IEA


Pathways (from Reactome)
Pathway description
Serotonin receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000592 short tail "reduced length of tail compared to control " [J:55583]
Show

Allelic Composition: Golga3tm1b(EUCOMM)Hmgu/Golga3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Golga3tm1b(EUCOMM)Hmgu/H

 MP:0001973 increased thermal nociceptive threshold "a greater than average point at which thermal pain sensation is first detectable" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, J:17194]
Show

Allelic Composition: Cfmq3129X1/SvJ/Cfmq3C57BL/6J,Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0002590 increased mean corpuscular volume "greater than the average amount of space occupied by each red blood cell, calculated from the hematocrit and red cell count, in erythrocyte indices" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Golga3tm1b(EUCOMM)Hmgu/Golga3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Golga3tm1b(EUCOMM)Hmgu/H

 MP:0005385 cardiovascular system phenotype 
Show

Allelic Composition: Golga3tm1b(EUCOMM)Hmgu/Golga3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Golga3tm1b(EUCOMM)Hmgu/H

 MP:0005633 increased circulating sodium level "greater than the normal concentration in the blood of this metallic element, the most plentiful extracellular ion in the body and the principal determinant of extracellular fluid volume" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Golga3tm1b(EUCOMM)Hmgu/Golga3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Golga3tm1b(EUCOMM)Hmgu/H

 MP:0009141 increased prepulse inhibition "increase in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cfmq3129X1/SvJ/Cfmq3C57BL/6J,Cftrtm1Unc/Cftrtm1Unc
Genetic Background: involves: 129X1/SvJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr