ENSMUSG00000070687


Mus musculus

Features
Gene ID: ENSMUSG00000070687
  
Biological name :Htr1d
  
Synonyms : 5-hydroxytryptamine (serotonin) receptor 1D / Htr1d / Q61224
  
Possible biological names infered from orthology : 5-hydroxytryptamine receptor 1D / P28221
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: D3
Gene start: 136423524
Gene end: 136444398
  
Corresponding Affymetrix probe sets: 10509238 (MoGene1.0st)   1422290_at (Mouse Genome 430 2.0 Array)   1440166_x_at (Mouse Genome 430 2.0 Array)   1440741_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000086052
Ensembl peptide - ENSMUSP00000112402
Ensembl peptide - ENSMUSP00000112840
NCBI entrez gene - 15552     See in Manteia.
MGI - MGI:96276
RefSeq - XM_017319986
RefSeq - NM_001285482
RefSeq - NM_001285483
RefSeq - NM_001285484
RefSeq - NM_008309
RefSeq - XM_006538577
RefSeq - XM_006538578
RefSeq Peptide - NP_032335
RefSeq Peptide - NP_001272411
RefSeq Peptide - NP_001272412
RefSeq Peptide - NP_001272413
swissprot - Q61224
Ensembl - ENSMUSG00000070687
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 htr1dENSDARG00000054124Danio rerio
 HTR1DENSGALG00000000820Gallus gallus
 HTR1DENSG00000179546Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Htr1b / P28334 / 5-hydroxytryptamine (serotonin) receptor 1B / P28222* / 5-hydroxytryptamine receptor 1B*ENSMUSG0000004951162
Htr1f / Q02284 / 5-hydroxytryptamine (serotonin) receptor 1F / P30939* / 5-hydroxytryptamine receptor 1F*ENSMUSG0000005078346
Htr1a / Q64264 / 5-hydroxytryptamine (serotonin) receptor 1A / P08908* / 5-hydroxytryptamine receptor 1A*ENSMUSG0000002172142
Htr7 / P32304 / 5-hydroxytryptamine (serotonin) receptor 7 / P34969* / 5-hydroxytryptamine receptor 7*ENSMUSG0000002479835
Adra2a / adrenoceptor alpha 2A / P08913*ENSMUSG0000003371732
Htr5b / 5-hydroxytryptamine (serotonin) receptor 5BENSMUSG0000005053432
Htr5a / P30966 / 5-hydroxytryptamine (serotonin) receptor 5A / P47898* / 5-hydroxytryptamine receptor 5A*ENSMUSG0000003910632
Adra2c / Q01337 / Alpha-2C adrenergic receptor / P18825* / adrenoceptor alpha 2C*ENSMUSG0000004531831
Adra1b / adrenoceptor alpha 1B / P35368*ENSMUSG0000005054131
Adra1a / P97718 / Alpha-1A adrenergic receptor / P35348* / adrenoceptor alpha 1A*ENSMUSG0000004587530
Adra2b / adrenoceptor alpha 2B / P18089*ENSMUSG0000005862030
Adra1d / adrenoceptor alpha 1D / P25100*ENSMUSG0000002733528


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000505  5-Hydroxytryptamine 1D receptor
 IPR002231  5-hydroxytryptamine receptor family
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006939 smooth muscle contraction IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway ISS
 biological_processGO:0007268 chemical synaptic transmission IEA
 biological_processGO:0009636 response to toxic substance IDA
 biological_processGO:0014827 intestine smooth muscle contraction ISO
 biological_processGO:0040012 regulation of locomotion IEA
 biological_processGO:0042310 vasoconstriction IEA
 biological_processGO:0050795 regulation of behavior IEA
 biological_processGO:0098664 G-protein coupled serotonin receptor signaling pathway IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004993 G-protein coupled serotonin receptor activity ISO
 molecular_functionGO:0030594 neurotransmitter receptor activity IBA
 molecular_functionGO:0051378 serotonin binding IDA


Pathways (from Reactome)
Pathway description
Serotonin receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Bcl2l1tm1Dlo/Bcl2l1tm1Dlo,Casp9tm1Flv/?
Genetic Background: involves: 129S1/Sv * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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