ENSG00000179546


Homo sapiens

Features
Gene ID: ENSG00000179546
  
Biological name :HTR1D
  
Synonyms : 5-hydroxytryptamine receptor 1D / HTR1D / P28221
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.12
Gene start: 23191895
Gene end: 23194729
  
Corresponding Affymetrix probe sets: 207368_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000363748
NCBI entrez gene - 3352     See in Manteia.
OMIM - 182133
RefSeq - NM_000864
RefSeq Peptide - NP_000855
swissprot - P28221
Ensembl - ENSG00000179546
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 htr1dENSDARG00000054124Danio rerio
 HTR1DENSGALG00000000820Gallus gallus
 Htr1dENSMUSG00000070687Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HTR1B / P28222 / 5-hydroxytryptamine receptor 1BENSG0000013531263
HTR1F / P30939 / 5-hydroxytryptamine receptor 1FENSG0000017909746
HTR1E / P28566 / 5-hydroxytryptamine receptor 1EENSG0000016883044
HTR1A / P08908 / 5-hydroxytryptamine receptor 1AENSG0000017839441
HTR7 / P34969 / 5-hydroxytryptamine receptor 7ENSG0000014868034
ADRA2C / P18825 / adrenoceptor alpha 2CENSG0000018416032
HTR5A / P47898 / 5-hydroxytryptamine receptor 5AENSG0000015721932
ADRA2A / P08913 / adrenoceptor alpha 2AENSG0000015059432
ADRA1B / P35368 / adrenoceptor alpha 1BENSG0000017021432
ADRA1A / P35348 / adrenoceptor alpha 1AENSG0000012090730
ADRA2B / P18089 / adrenoceptor alpha 2BENSG0000027428630
ADRA1D / P25100 / adrenoceptor alpha 1DENSG0000017187328


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000505  5-Hydroxytryptamine 1D receptor
 IPR002231  5-hydroxytryptamine receptor family
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006939 smooth muscle contraction IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger TAS
 biological_processGO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway IMP
 biological_processGO:0007268 chemical synaptic transmission TAS
 biological_processGO:0009636 response to toxic substance IEA
 biological_processGO:0014827 intestine smooth muscle contraction IMP
 biological_processGO:0040012 regulation of locomotion IEA
 biological_processGO:0042310 vasoconstriction IEA
 biological_processGO:0050795 regulation of behavior IEA
 biological_processGO:0098664 G-protein coupled serotonin receptor signaling pathway IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004993 G-protein coupled serotonin receptor activity TAS
 molecular_functionGO:0030594 neurotransmitter receptor activity IBA
 molecular_functionGO:0051378 serotonin binding IEA


Pathways (from Reactome)
Pathway description
Serotonin receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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