ENSG00000148680


Homo sapiens

Features
Gene ID: ENSG00000148680
  
Biological name :HTR7
  
Synonyms : 5-hydroxytryptamine receptor 7 / HTR7 / P34969
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q23.31
Gene start: 90740823
Gene end: 90857698
  
Corresponding Affymetrix probe sets: 207818_s_at (Human Genome U133 Plus 2.0 Array)   207927_at (Human Genome U133 Plus 2.0 Array)   216098_s_at (Human Genome U133 Plus 2.0 Array)   236281_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000277874
Ensembl peptide - ENSP00000337949
Ensembl peptide - ENSP00000360784
NCBI entrez gene - 3363     See in Manteia.
OMIM - 182137
RefSeq - NM_019859
RefSeq - NM_000872
RefSeq - NM_019860
RefSeq Peptide - NP_000863
RefSeq Peptide - NP_062873
RefSeq Peptide - NP_062874
swissprot - P34969
Ensembl - ENSG00000148680
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FO704724.1ENSDARG00000099854Danio rerio
 htr7aENSDARG00000056949Danio rerio
 HTR7ENSGALG00000040549Gallus gallus
 Htr7ENSMUSG00000024798Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADRA1B / P35368 / adrenoceptor alpha 1BENSG0000017021428
HTR1B / P28222 / 5-hydroxytryptamine receptor 1BENSG0000013531228
ADRA1D / P25100 / adrenoceptor alpha 1DENSG0000017187328
HTR1E / P28566 / 5-hydroxytryptamine receptor 1EENSG0000016883027
HTR1F / P30939 / 5-hydroxytryptamine receptor 1FENSG0000017909727
HTR1A / P08908 / 5-hydroxytryptamine receptor 1AENSG0000017839427
HTR1D / P28221 / 5-hydroxytryptamine receptor 1DENSG0000017954627
ADRA1A / P35348 / adrenoceptor alpha 1AENSG0000012090726
HTR5A / P47898 / 5-hydroxytryptamine receptor 5AENSG0000015721924
ADRA2B / P18089 / adrenoceptor alpha 2BENSG0000027428623
ADRA2A / P08913 / adrenoceptor alpha 2AENSG0000015059423
ADRA2C / P18825 / adrenoceptor alpha 2CENSG0000018416023


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR001069  5-Hydroxytryptamine 7 receptor
 IPR002231  5-hydroxytryptamine receptor family
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006939 smooth muscle contraction IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger TAS
 biological_processGO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway IBA
 biological_processGO:0007268 chemical synaptic transmission TAS
 biological_processGO:0007623 circadian rhythm TAS
 biological_processGO:0008015 blood circulation TAS
 biological_processGO:0042310 vasoconstriction IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004993 G-protein coupled serotonin receptor activity TAS
 molecular_functionGO:0030594 neurotransmitter receptor activity IBA
 molecular_functionGO:0051378 serotonin binding IBA


Pathways (from Reactome)
Pathway description
Serotonin receptors
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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