ENSDARG00000025641


Danio rerio

Features
Gene ID: ENSDARG00000025641
  
Biological name :gli2a
  
Synonyms : gli2a / GLI family zinc finger 2a
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 37141836
Gene end: 37297485
  
Corresponding Affymetrix probe sets: Dr.8091.1.S1_at (Zebrafish Array)   NM_130967_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000154006
Ensembl peptide - ENSDARP00000010693
NCBI entrez gene - 30154     See in Manteia.
RefSeq - NM_130967
RefSeq Peptide - NP_571042
swissprot - B0S6T1
ZFIN ID - ZDB-GENE-990706-8
Ensembl - ENSDARG00000025641
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gli2b / GLI family zinc finger 2b / GLI2* / P10070* / GLI family zinc finger 2*ENSDARG0000002088452
gli3 / GLI family zinc finger 3ENSDARG0000005213142
gli1 / GLI family zinc finger 1 / P08151*ENSDARG0000010124436
glis3 / GLIS family zinc finger 3 / Q6XP49* / Q8NEA6* / Zinc finger protein GLIS3 *ENSDARG0000006972613
glis1b / GLIS family zinc finger 1b / GLIS1* / Q8K1M4* / Q8NBF1* / GLIS family zinc finger 1* / Zinc finger protein GLIS1 *ENSDARG0000002793311
glis2b / GLIS family zinc finger 2b / GLIS2* / Q8VDL9* / Q9BZE0* / GLIS family zinc finger 2* / Zinc finger protein GLIS2 *ENSDARG0000010023211
zic4 / zic family member 4 / Q61467* / Q8N9L1* / zinc finger protein of the cerebellum 4*ENSDARG0000003130710
zic5 / zic family member 5 (odd-paired homolog, Drosophila) / Q96T25* / Zic family member 5* / zinc finger protein of the cerebellum 5*ENSDARG0000001602210
glis1a / GLIS family zinc finger 1a / GLIS1* / Q8K1M4* / Q8NBF1* / GLIS family zinc finger 1* / Zinc finger protein GLIS1 *ENSDARG0000006858010
zic1 / zic family member 1 (odd-paired homolog, Drosophila)ENSDARG000000155679
zic6 / zic family member 6ENSDARG000000714969
zic2b / zic family member 2 (odd-paired homolog, Drosophila) b / ZIC2* / O95409* / Zic family member 2* / zinc finger protein of the cerebellum 2*ENSDARG000000371789
zic3 / zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila) / Q62521* / O60481* / Zic family member 3* / zinc finger protein of the cerebellum 3*ENSDARG000000714979
zic2a / zic family member 2 (odd-paired homolog, Drosophila), a / ZIC2* / O95409* / Zic family member 2* / zinc finger protein of the cerebellum 2*ENSDARG000000155549
glis2a / GLIS family zinc finger 2a / GLIS2* / Q9BZE0* / GLIS family zinc finger 2*ENSDARG000000783889
si:dkey-149i17.7ENSDARG000000946845


Protein motifs (from Interpro)
Interpro ID Name
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001756 somitogenesis IMP
 biological_processGO:0007224 smoothened signaling pathway IDA
 biological_processGO:0007399 nervous system development IMP
 biological_processGO:0007411 axon guidance IMP
 biological_processGO:0007420 brain development IMP
 biological_processGO:0007517 muscle organ development IMP
 biological_processGO:0008015 blood circulation IMP
 biological_processGO:0008045 motor neuron axon guidance IMP
 biological_processGO:0009953 dorsal/ventral pattern formation IMP
 biological_processGO:0021508 floor plate formation IMP
 biological_processGO:0021523 somatic motor neuron differentiation IMP
 biological_processGO:0021532 neural tube patterning IMP
 biological_processGO:0021634 optic nerve formation IMP
 biological_processGO:0021953 central nervous system neuron differentiation IMP
 biological_processGO:0021983 pituitary gland development IMP
 biological_processGO:0021984 adenohypophysis development IMP
 biological_processGO:0031018 endocrine pancreas development IMP
 biological_processGO:0031290 retinal ganglion cell axon guidance IMP
 biological_processGO:0032835 glomerulus development IMP
 biological_processGO:0042476 odontogenesis IMP
 biological_processGO:0042694 muscle cell fate specification IMP
 biological_processGO:0048557 embryonic digestive tract morphogenesis IMP
 biological_processGO:0048618 post-embryonic foregut morphogenesis IMP
 biological_processGO:0048793 pronephros development IMP
 biological_processGO:0048855 adenohypophysis morphogenesis IMP
 biological_processGO:0050767 regulation of neurogenesis IMP
 biological_processGO:0055002 striated muscle cell development IMP
 biological_processGO:0070935 3"-UTR-mediated mRNA stabilization IGI
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0097730 non-motile cilium IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000003 adaxial cell adaxial cell absent , abnormal
adaxial cell disorganized , abnormal
adaxial cell physical object quality , abnormal
adaxial cell decreased amount , abnormal
Show

 ZFA:0000008 brain brain quality , abnormal
Show

 ZFA:0000014 dorsal aorta dorsal aorta morphology , abnormal
Show

 ZFA:0000022 floor plate floor plate hypoplastic , abnormal
Show

 ZFA:0000029 hindbrain hindbrain quality , abnormal
Show

 ZFA:0000035 lens lens increased amount , abnormal
lens mislocalised , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000059 postoptic commissure postoptic commissure absent , abnormal
Show

 ZFA:0000066 proctodeum proctodeum malformed , abnormal
proctodeum atretic , abnormal
Show

 ZFA:0000107 eye eye decreased distance eye , abnormal
eye mislocalised medially , abnormal
Show

 ZFA:0000109 forebrain forebrain physical object quality , abnormal
Show

 ZFA:0000155 somite somite has fewer parts of type slow muscle cell , abnormal
somite U-shaped , abnormal
somite quality , abnormal
somite lacks all parts of type muscle pioneer , abnormal
somite has extra parts of type muscle precursor cell , abnormal
somite lacks parts or has fewer parts of type muscle pioneer , abnormal
somite lacks parts or has fewer parts of type slow muscle cell , abnormal
somite lacks all parts of type slow muscle cell , abnormal
somite morphology , abnormal
somite malformed , abnormal
somite fused with somite , abnormal
Show

 ZFA:0000161 third ventricle third ventricle increased size , abnormal
Show

 ZFA:0000204 esophagus esophagus malformed , abnormal
Show

 ZFA:0000206 facial nerve motor nucleus facial nerve motor nucleus decreased amount , abnormal
facial nerve motor nucleus mislocalised anteriorly , abnormal
Show

 ZFA:0000297 vagal lobe vagal lobe aplastic , abnormal
Show

 ZFA:0000396 nervous system nervous system quality , abnormal
Show

 ZFA:0000477 posterior cardinal vein posterior cardinal vein morphology , abnormal
Show

 ZFA:0000556 optic chiasm optic chiasm malformed , abnormal
optic chiasm absent , abnormal
Show

 ZFA:0000671 horizontal myoseptum horizontal myoseptum aplastic , abnormal
horizontal myoseptum absent , abnormal
horizontal myoseptum morphology , abnormal
horizontal myoseptum hypoplastic , abnormal
Show

 ZFA:0000694 ceratobranchial 5 tooth ceratobranchial 5 tooth decreased length , abnormal
ceratobranchial 5 tooth increased width , abnormal
Show

 ZFA:0001056 myotome myotome malformed , abnormal
myotome decreased distribution , abnormal
Show

 ZFA:0001086 muscle pioneer muscle pioneer absent , abnormal
muscle pioneer decreased amount , abnormal
muscle pioneer mislocalised , abnormal
Show

 ZFA:0001089 myoseptum myoseptum aplastic , abnormal
myoseptum quality , abnormal
Show

 ZFA:0001094 whole organism whole organism curved ventral , abnormal
whole organism lethal (sensu genetics) , abnormal
whole organism movement behavioral quality , abnormal
whole organism decreased behavioural activity , abnormal
Show

 ZFA:0001108 anterior commissure anterior commissure decreased size , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved ventral , abnormal
post-vent region curved , abnormal
Show

 ZFA:0001135 neural tube neural tube quality , abnormal
Show

 ZFA:0001195 pars anterior pars anterior physical object quality , abnormal
Show

 ZFA:0001239 ceratobranchial 5 bone ceratobranchial 5 bone decreased length , abnormal
ceratobranchial 5 bone has fewer parts of type ceratobranchial 5 tooth , abnormal
Show

 ZFA:0001256 lateral floor plate lateral floor plate composition , abnormal
Show

 ZFA:0001282 adenohypophysis adenohypophysis aplastic , abnormal
adenohypophysis physical object quality , abnormal
adenohypophysis wholly anterioralized , abnormal
Show

 ZFA:0001365 trigeminal motor nucleus trigeminal motor nucleus aplastic , abnormal
Show

 ZFA:0001405 ethmoid cartilage ethmoid cartilage aplastic , abnormal
Show

 ZFA:0001424 chondrocranium chondrocranium morphology , abnormal
Show

 ZFA:0001499 esophageal epithelium esophageal epithelium disorganized , abnormal
esophageal epithelium epithelial cell differentiation disrupted , abnormal
Show

 ZFA:0001507 trabecula cranii trabecula cranii fused with trabecula cranii , abnormal
Show

 ZFA:0001557 pronephric glomerulus pronephric glomerulus increased amount , abnormal
pronephric glomerulus mislocalised laterally , abnormal
Show

 ZFA:0001613 pharyngeal arch 3-7 pharyngeal arch 3-7 mislocalised ventrally , abnormal
Show

 ZFA:0005179 MiP motor neuron MiP motor neuron axon decreased amount , abnormal
Show

 ZFA:0009003 cranial neural crest cell cranial neural crest cell mislocalised ventrally , abnormal
Show

 ZFA:0009053 sensory neuron sensory neuron morphology , abnormal
sensory neuron mislocalised , abnormal
Show

 ZFA:0009116 slow muscle cell slow muscle cell absent , abnormal
slow muscle cell decreased amount , abnormal
slow muscle cell mislocalised , abnormal
Show

 ZFA:0009117 fast muscle cell fast muscle cell absent , abnormal
fast muscle cell increased amount , abnormal
fast muscle cell decreased amount , abnormal
Show

 ZFA:0009150 Rohon-Beard neuron Rohon-Beard neuron decreased amount , abnormal
Rohon-Beard neuron morphology , abnormal
Show

 ZFA:0009155 somatotropin secreting cell somatotropin secreting cell decreased amount , abnormal
Show

 ZFA:0009204 prolactin secreting cell prolactin secreting cell decreased amount , abnormal
prolactin secreting cell increased amount , abnormal
Show

 ZFA:0009205 melanocyte stimulating hormone secreting cell melanocyte stimulating hormone secreting cell decreased amount , abnormal
Show

 ZFA:0009216 adrenocorticotropic hormone secreting cell adrenocorticotropic hormone secreting cell decreased amount , abnormal
Show

 ZFA:0009218 thyroid stimulating hormone secreting cell thyroid stimulating hormone secreting cell decreased amount , abnormal
Show

 ZFA:0009243 CaP motoneuron CaP motoneuron axon decreased amount , abnormal
Show

 ZFA:0009310 retinal ganglion cell retinal ganglion cell axon misrouted , abnormal
retinal ganglion cell axon ipsilateral to eye , abnormal
retinal ganglion cell axon displaced to diencephalon , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   


© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr