ENSDARG00000020884


Danio rerio

Features
Gene ID: ENSDARG00000020884
  
Biological name :gli2b
  
Synonyms : gli2b / GLI family zinc finger 2b
  
Possible biological names infered from orthology : GLI2 / GLI family zinc finger 2 / P10070 / Q0VGT2 / Zinc finger protein GLI2
  
Species: Danio rerio
  
Chr. number: 11
Strand: 1
Band:
Gene start: 43661735
Gene end: 43713750
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000015266
swissprot - F1QH64
ZFIN ID - ZDB-GENE-050523-1
Ensembl - ENSDARG00000020884
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GLI2ENSGALG00000011630Gallus gallus
 GLI2ENSG00000074047Homo sapiens
 Gli2ENSMUSG00000048402Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gli2a / GLI family zinc finger 2aENSDARG0000002564161
gli3 / GLI family zinc finger 3ENSDARG0000005213141
gli1 / GLI family zinc finger 1 / P08151*ENSDARG0000010124438
glis3 / GLIS family zinc finger 3 / Q6XP49* / Q8NEA6* / Zinc finger protein GLIS3 *ENSDARG0000006972615
glis1b / GLIS family zinc finger 1b / GLIS1* / Q8K1M4* / Q8NBF1* / GLIS family zinc finger 1* / Zinc finger protein GLIS1 *ENSDARG0000002793312
glis1a / GLIS family zinc finger 1a / GLIS1* / Q8K1M4* / Q8NBF1* / GLIS family zinc finger 1* / Zinc finger protein GLIS1 *ENSDARG0000006858011
glis2b / GLIS family zinc finger 2b / GLIS2* / Q8VDL9* / Q9BZE0* / GLIS family zinc finger 2* / Zinc finger protein GLIS2 *ENSDARG0000010023211
zic5 / zic family member 5 (odd-paired homolog, Drosophila) / Q96T25* / Zic family member 5* / zinc finger protein of the cerebellum 5*ENSDARG0000001602210
zic1 / zic family member 1 (odd-paired homolog, Drosophila)ENSDARG0000001556710
zic6 / zic family member 6ENSDARG0000007149610
zic4 / zic family member 4 / Q61467* / Q8N9L1* / zinc finger protein of the cerebellum 4*ENSDARG0000003130710
zic3 / zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila) / Q62521* / O60481* / Zic family member 3* / zinc finger protein of the cerebellum 3*ENSDARG0000007149710
zic2b / zic family member 2 (odd-paired homolog, Drosophila) b / ZIC2* / O95409* / Zic family member 2* / zinc finger protein of the cerebellum 2*ENSDARG0000003717810
zic2a / zic family member 2 (odd-paired homolog, Drosophila), a / ZIC2* / O95409* / Zic family member 2* / zinc finger protein of the cerebellum 2*ENSDARG0000001555410
glis2a / GLIS family zinc finger 2a / GLIS2* / Q9BZE0* / GLIS family zinc finger 2*ENSDARG0000007838810
si:dkey-149i17.7ENSDARG000000946846


Protein motifs (from Interpro)
Interpro ID Name
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009953 dorsal/ventral pattern formation IMP
 biological_processGO:0021508 floor plate formation IMP
 biological_processGO:0021534 cell proliferation in hindbrain IMP
 biological_processGO:0021953 central nervous system neuron differentiation IMP
 biological_processGO:0048855 adenohypophysis morphogenesis IMP
 molecular_functionGO:0003676 nucleic acid binding IEA


Pathways (from Reactome)
Pathway description
Hedgehog off state
Hedgehog on state


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain decreased size , abnormal
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 ZFA:0000029 hindbrain hindbrain astrocyte decreased amount , abnormal
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 ZFA:0000110 fourth ventricle fourth ventricle increased size , abnormal
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 ZFA:0000206 facial nerve motor nucleus facial nerve motor nucleus mislocalised laterally , abnormal
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 ZFA:0000713 abducens motor nucleus abducens motor nucleus aplastic , abnormal
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 ZFA:0001195 pars anterior pars anterior physical object quality , abnormal
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 ZFA:0001258 floor plate rhombomere region floor plate rhombomere region increased width , abnormal
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 ZFA:0001282 adenohypophysis adenohypophysis physical object quality , abnormal
adenohypophysis wholly anterioralized , abnormal
Show

 ZFA:0001365 trigeminal motor nucleus trigeminal motor nucleus mislocalised laterally , abnormal
Show

 ZFA:0009150 Rohon-Beard neuron Rohon-Beard neuron decreased amount , abnormal
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 ZFA:0009155 somatotropin secreting cell somatotropin secreting cell decreased amount , abnormal
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 ZFA:0009204 prolactin secreting cell prolactin secreting cell decreased amount , abnormal
prolactin secreting cell increased amount , abnormal
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 ZFA:0009205 melanocyte stimulating hormone secreting cell melanocyte stimulating hormone secreting cell decreased amount , abnormal
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 ZFA:0009216 adrenocorticotropic hormone secreting cell adrenocorticotropic hormone secreting cell decreased amount , abnormal
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 ZFA:0009218 thyroid stimulating hormone secreting cell thyroid stimulating hormone secreting cell increased amount , abnormal
Show

 ZFA:0009247 secondary motor neuron secondary motor neuron decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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