ENSDARG00000015554


Danio rerio

Features
Gene ID: ENSDARG00000015554
  
Biological name :zic2a
  
Synonyms : zic2a / zic family member 2 (odd-paired homolog, Drosophila), a
  
Possible biological names infered from orthology : O95409 / ZIC2 / Zic family member 2 / zinc finger protein of the cerebellum 2
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 31282161
Gene end: 31287010
  
Corresponding Affymetrix probe sets: Dr.4807.1.S1_at (Zebrafish Array)   Dr.4807.1.S2_at (Zebrafish Array)   NM_131558_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000026131
NCBI entrez gene - 58077     See in Manteia.
RefSeq - NM_131558
RefSeq Peptide - NP_571633
swissprot - Q9IAT0
ZFIN ID - ZDB-GENE-000710-4
Ensembl - ENSDARG00000015554
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ZIC2ENSGALG00000041083Gallus gallus
 ZIC2ENSG00000043355Homo sapiens
 Zic2ENSMUSG00000061524Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
zic2b / zic family member 2 (odd-paired homolog, Drosophila) b / ZIC2* / O95409* / Zic family member 2* / zinc finger protein of the cerebellum 2*ENSDARG0000003717878
zic1 / zic family member 1 (odd-paired homolog, Drosophila)ENSDARG0000001556773
zic3 / zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila) / Q62521* / O60481* / Zic family member 3* / zinc finger protein of the cerebellum 3*ENSDARG0000007149768
zic4 / zic family member 4 / Q61467* / Q8N9L1* / zinc finger protein of the cerebellum 4*ENSDARG0000003130757
zic5 / zic family member 5 (odd-paired homolog, Drosophila) / Q96T25* / Zic family member 5* / zinc finger protein of the cerebellum 5*ENSDARG0000001602251
zic6 / zic family member 6ENSDARG0000007149642
gli3 / GLI family zinc finger 3ENSDARG0000005213131
gli2a / GLI family zinc finger 2aENSDARG0000002564130
gli2b / GLI family zinc finger 2b / GLI2* / P10070* / GLI family zinc finger 2*ENSDARG0000002088429
gli1 / GLI family zinc finger 1 / P08151*ENSDARG0000010124428
glis3 / GLIS family zinc finger 3 / Q6XP49* / Q8NEA6* / Zinc finger protein GLIS3 *ENSDARG0000006972625
glis1b / GLIS family zinc finger 1b / GLIS1* / Q8K1M4* / Q8NBF1* / GLIS family zinc finger 1* / Zinc finger protein GLIS1 *ENSDARG0000002793322
glis1a / GLIS family zinc finger 1a / GLIS1* / Q8K1M4* / Q8NBF1* / GLIS family zinc finger 1* / Zinc finger protein GLIS1 *ENSDARG0000006858021
glis2a / GLIS family zinc finger 2a / GLIS2* / Q9BZE0* / GLIS family zinc finger 2*ENSDARG0000007838820
glis2b / GLIS family zinc finger 2b / GLIS2* / Q8VDL9* / Q9BZE0* / GLIS family zinc finger 2* / Zinc finger protein GLIS2 *ENSDARG0000010023220
si:dkey-149i17.7ENSDARG0000009468420


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001841 neural tube formation IGI
 biological_processGO:0008589 regulation of smoothened signaling pathway IMP
 biological_processGO:0009953 dorsal/ventral pattern formation IMP
 biological_processGO:0014032 neural crest cell development IMP
 biological_processGO:0021536 diencephalon development IMP
 biological_processGO:0021846 cell proliferation in forebrain IMP
 biological_processGO:0030901 midbrain development IMP
 biological_processGO:0030902 hindbrain development IGI
 biological_processGO:0033278 cell proliferation in midbrain IMP
 biological_processGO:0042127 regulation of cell proliferation IMP
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IMP
 biological_processGO:0048385 regulation of retinoic acid receptor signaling pathway IGI
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 biological_processGO:0060059 embryonic retina morphogenesis in camera-type eye IMP
 molecular_functionGO:0003676 nucleic acid binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000029 hindbrain hindbrain malformed , abnormal
Show

 ZFA:0000032 hypothalamus hypothalamus cellular quality , abnormal
Show

 ZFA:0000046 retinal neural layer retinal neural layer decreased size , abnormal
Show

 ZFA:0000110 fourth ventricle fourth ventricle malformed , abnormal
Show

 ZFA:0000128 midbrain midbrain malformed , abnormal
Show

 ZFA:0000159 tectal ventricle tectal ventricle malformed , abnormal
Show

 ZFA:0000458 ventral thalamus ventral thalamus cellular quality , abnormal
ventral thalamus decreased size , abnormal
Show

 ZFA:0001114 head head has fewer parts of type xanthoblast , abnormal
Show

 ZFA:0001115 trunk trunk has fewer parts of type xanthoblast , abnormal
Show

 ZFA:0001135 neural tube neural tube malformed , abnormal
Show

 ZFA:0001194 cranial neural crest cranial neural crest mislocalised dorsally , abnormal
Show

 ZFA:0001273 ventral mandibular arch ventral mandibular arch malformed , abnormal
Show

 ZFA:0001284 optic fissure optic fissure malformed , abnormal
optic fissure closure incomplete , abnormal
Show

 ZFA:0001290 stomodeum stomodeum decreased size , abnormal
Show

 ZFA:0001306 pharyngeal arch pharyngeal arch cellular quality , abnormal
Show

 ZFA:0001321 neurocranial trabecula neurocranial trabecula shortened , abnormal
Show

 ZFA:0001405 ethmoid cartilage ethmoid cartilage medial region absent , abnormal
Show

 ZFA:0001460 pharyngeal arch cartilage pharyngeal arch cartilage hypoplastic , abnormal
Show

 ZFA:0001611 pharyngeal arch 2 pharyngeal arch 2 decreased size , abnormal
pharyngeal arch 2 malformed , abnormal
Show

 ZFA:0001612 pharyngeal arch 1 pharyngeal arch 1 decreased size , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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