ENSDARG00000037383


Danio rerio

Features
Gene ID: ENSDARG00000037383
  
Biological name :pax5
  
Synonyms : paired box 5 / pax5
  
Possible biological names infered from orthology : Paired box protein Pax-5 / Q02548 / Q02650
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 21725821
Gene end: 21815554
  
Corresponding Affymetrix probe sets: Dr.8176.1.A1_at (Zebrafish Array)   Dr.8176.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000114412
Ensembl peptide - ENSDARP00000054394
NCBI entrez gene - 60636     See in Manteia.
RefSeq - NM_131638
RefSeq Peptide - NP_571713
swissprot - F1QGF8
swissprot - F1Q6J2
ZFIN ID - ZDB-GENE-001030-2
Ensembl - ENSDARG00000037383
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PAX5ENSGALG00000016431Gallus gallus
 PAX5ENSG00000196092Homo sapiens
 Pax5ENSMUSG00000014030Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pax2a / Q90268 / paired box 2a / PAX2* / Q02962* / paired box 2*ENSDARG0000002814863
pax2b / paired box 2b / PAX2* / Q02962* / paired box 2*ENSDARG0000003257861
pax8 / paired box 8 / Q06710*ENSDARG0000001587952
pax6a / P26630 / paired box 6aENSDARG0000010337935
pax7b / paired box 7b / PAX7* / P47239* / P23759* / paired box 7* / Paired box protein Pax-7 *ENSDARG0000007081834
pax7a / paired box 7a / PAX7* / P23759* / paired box 7*ENSDARG0000010039834
pax6b / paired box 6bENSDARG0000004593634
pax3a / paired box 3a / PAX3* / P23760* / P24610* / paired box 3*ENSDARG0000001019233
pax1a / paired box 1a / PAX1* / P15863* / paired box 1*ENSDARG0000000820332
pax3b / paired box 3b / PAX3* / P23760* / paired box 3*ENSDARG0000002834832
pax1b / paired box 1b / PAX1* / P15863* / P09084* / paired box 1* / Paired box protein Pax-1 *ENSDARG0000007381431
pax9 / paired box 9 / P47242* / P55771* / Paired box protein Pax-9 *ENSDARG0000005382931
pax4 / paired box 4 / O43316* / P32115*ENSDARG0000002133625


Protein motifs (from Interpro)
Interpro ID Name
 IPR001523  Paired domain
 IPR009057  Homeobox-like domain superfamily
 IPR011991  ArsR-like helix-turn-helix domain
 IPR022130  Paired-box protein 2 C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0060005 vestibular reflex IMP
 biological_processGO:0060118 vestibular receptor cell development IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA


Pathways (from Reactome)
Pathway description
RUNX1 regulates transcription of genes involved in BCR signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000030 macula utricle macula utricle hair cell irregular spatial pattern , abnormal
Show

 ZFA:0000700 utricle utricle hair cell morphology , abnormal
utricle lacks parts or has fewer parts of type hair cell , abnormal
Show

 ZFA:0009366 hair cell hair cell mislocalised , abnormal
hair cell apoptotic , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000087646 runx1 / runt-related transcription factor 1 / Q01196*  / reaction / complex






 

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