ENSDARG00000015879


Danio rerio

Features
Gene ID: ENSDARG00000015879
  
Biological name :pax8
  
Synonyms : paired box 8 / pax8
  
Possible biological names infered from orthology : Paired box protein Pax-8 / Q00288 / Q06710
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 72407526
Gene end: 72415578
  
Corresponding Affymetrix probe sets: Dr.8177.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000033414
NCBI entrez gene - 60637     See in Manteia.
swissprot - F1Q9Q9
ZFIN ID - ZDB-GENE-001030-3
Ensembl - ENSDARG00000015879
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PAX8ENSG00000125618Homo sapiens
 Pax8ENSMUSG00000026976Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pax2a / Q90268 / paired box 2a / PAX2* / Q02962* / paired box 2*ENSDARG0000002814852
pax2b / paired box 2b / PAX2* / Q02962* / paired box 2*ENSDARG0000003257851
pax5 / paired box 5 / Q02548* / Q02650* / Paired box protein Pax-5 *ENSDARG0000003738346
pax7a / paired box 7a / PAX7* / P23759* / paired box 7*ENSDARG0000010039832
pax7b / paired box 7b / PAX7* / P47239* / P23759* / paired box 7* / Paired box protein Pax-7 *ENSDARG0000007081832
pax6a / P26630 / paired box 6aENSDARG0000010337931
pax3a / paired box 3a / PAX3* / P23760* / P24610* / paired box 3*ENSDARG0000001019230
pax6b / paired box 6bENSDARG0000004593630
pax3b / paired box 3b / PAX3* / P23760* / paired box 3*ENSDARG0000002834828
pax1a / paired box 1a / PAX1* / P15863* / paired box 1*ENSDARG0000000820327
pax1b / paired box 1b / PAX1* / P15863* / P09084* / paired box 1* / Paired box protein Pax-1 *ENSDARG0000007381427
pax9 / paired box 9 / P47242* / P55771* / Paired box protein Pax-9 *ENSDARG0000005382927
pax4 / paired box 4 / O43316* / P32115*ENSDARG0000002133623


Protein motifs (from Interpro)
Interpro ID Name
 IPR001523  Paired domain
 IPR009057  Homeobox-like domain superfamily
 IPR011991  ArsR-like helix-turn-helix domain
 IPR022130  Paired-box protein 2 C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007422 peripheral nervous system development IGI
 biological_processGO:0034672 anterior/posterior pattern specification involved in pronephros development IGI
 biological_processGO:0043049 otic placode formation IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary decreased width , abnormal
Show

 ZFA:0000051 otic vesicle otic vesicle decreased size , abnormal
otic vesicle has fewer parts of type hair cell , abnormal
Show

 ZFA:0000138 otic placode otic placode physical object quality , abnormal
Show

 ZFA:0000166 lateral crista lateral crista physical object quality , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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