ENSDARG00000021336


Danio rerio

Features
Gene ID: ENSDARG00000021336
  
Biological name :pax4
  
Synonyms : paired box 4 / pax4
  
Possible biological names infered from orthology : O43316 / P32115
  
Species: Danio rerio
  
Chr. number: 4
Strand: 1
Band:
Gene start: 19700308
Gene end: 19704628
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000013792
NCBI entrez gene - 561564     See in Manteia.
RefSeq - NM_001245080
RefSeq Peptide - NP_001232009
swissprot - F1R840
ZFIN ID - ZDB-GENE-041210-244
Ensembl - ENSDARG00000021336
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PAX4ENSG00000106331Homo sapiens
 Pax4ENSMUSG00000029706Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pax7a / paired box 7a / PAX7* / P23759* / paired box 7*ENSDARG0000010039831
pax6a / P26630 / paired box 6aENSDARG0000010337931
pax6b / paired box 6bENSDARG0000004593631
pax2a / Q90268 / paired box 2a / PAX2* / Q02962* / paired box 2*ENSDARG0000002814831
pax7b / paired box 7b / PAX7* / P47239* / P23759* / paired box 7* / Paired box protein Pax-7 *ENSDARG0000007081831
pax2b / paired box 2b / PAX2* / Q02962* / paired box 2*ENSDARG0000003257831
pax8 / paired box 8 / Q06710*ENSDARG0000001587929
pax5 / paired box 5 / Q02548* / Q02650* / Paired box protein Pax-5 *ENSDARG0000003738329
pax3b / paired box 3b / PAX3* / P23760* / paired box 3*ENSDARG0000002834828
pax3a / paired box 3a / PAX3* / P23760* / P24610* / paired box 3*ENSDARG0000001019228
pax1a / paired box 1a / PAX1* / P15863* / paired box 1*ENSDARG0000000820326
pax1b / paired box 1b / PAX1* / P15863* / P09084* / paired box 1* / Paired box protein Pax-1 *ENSDARG0000007381424
pax9 / paired box 9 / P47242* / P55771* / Paired box protein Pax-9 *ENSDARG0000005382924


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR001523  Paired domain
 IPR009057  Homeobox-like domain superfamily
 IPR011991  ArsR-like helix-turn-helix domain
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0031018 endocrine pancreas development IMP
 biological_processGO:0042593 glucose homeostasis IMP
 biological_processGO:1990798 pancreas regeneration IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001260 endocrine pancreas endocrine pancreas decreased size , abnormal
endocrine pancreas decreased distribution , abnormal
Show

 ZFA:0005598 pancreatic epsilon cell pancreatic epsilon cell increased amount , abnormal
Show

 ZFA:0005599 ghrelin secreting cell ghrelin secreting cell increased amount , abnormal
Show

 ZFA:0009102 pancreatic B cell pancreatic B cell decreased amount , abnormal
pancreatic B cell decreased area , abnormal
pancreatic B cell regeneration decreased rate , abnormal
Show

 ZFA:0009103 glucagon secreting cell glucagon secreting cell increased amount , abnormal
Show

 ZFA:0009104 pancreatic A cell pancreatic A cell increased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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