ENSDARG00000103490


Danio rerio

Features
Gene ID: ENSDARG00000103490
  
Biological name :dpysl4
  
Synonyms : dihydropyrimidinase-like 4 / dpysl4
  
Possible biological names infered from orthology : O14531
  
Species: Danio rerio
  
Chr. number: 12
Strand: -1
Band:
Gene start: 41580783
Gene end: 41619257
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000132515
Ensembl peptide - ENSDARP00000141349
NCBI entrez gene - 553411     See in Manteia.
swissprot - A0A0R4IYX8
swissprot - A0A0R4IBZ8
swissprot - A0A0R4IL21
ZFIN ID - ZDB-GENE-050720-3
Ensembl - ENSDARG00000103490
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DPYSL4ENSGALG00000010490Gallus gallus
 DPYSL4ENSG00000151640Homo sapiens
 Dpysl4ENSMUSG00000025478Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DPYSL2 (1 of many) / dihydropyrimidinase like 2 / DPYSL2* / Q16555*ENSDARG0000003897472
dpysl2b / dihydropyrimidinase-like 2b / Q16555* / DPYSL2* / O08553* / dihydropyrimidinase like 2* / Dihydropyrimidinase-related protein 2 *ENSDARG0000003208369
crmp1 / collapsin response mediator protein 1 / Q14194*ENSDARG0000005674265
dpysl3 / Q52PJ5 / dihydropyrimidinase-like 3 / Q14195*ENSDARG0000000258764
dpys / dihydropyrimidinase / Q14117* / Q9EQF5*ENSDARG0000007954349
dpysl5b / dihydropyrimidinase-like 5bENSDARG0000005931148
dpysl5a / dihydropyrimidinase-like 5aENSDARG0000001114147
zgc:103559ENSDARG0000003829316


Protein motifs (from Interpro)
Interpro ID Name
 IPR006680  Amidohydrolase-related
 IPR011059  Metal-dependent hydrolase, composite domain superfamily
 IPR011778  Hydantoinase/dihydropyrimidinase
 IPR030612  Dihydropyrimidinase-related protein 4
 IPR030624  Dihydropyrimidinase-related protein 1
 IPR032466  Metal-dependent hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0070997 neuron death IEA
 biological_processGO:0097485 neuron projection guidance IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds IEA


Pathways (from Reactome)
Pathway description
CRMPs in Sema3A signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000017803 gsk3b / glycogen synthase kinase 3 beta / P49841* / Q9WV60*  / reaction
 ENSDARG00000019328 plxna4 / plexin A4 / Q80UG2* / Q9HCM2*  / reaction / complex
 ENSDARG00000007172 plxna3 / plexin A3 / P51805* / P70208*  / reaction / complex
 ENSDARG00000025319 fynb / F1RDG9 / FYN proto-oncogene, Src family tyrosine kinase b / FYN* / P39688* / P06241* / Tyrosine-protein kinase Fyn * / FYN proto-oncogene, Src family tyrosine kinase*  / reaction / complex
 ENSDARG00000002587 dpysl3 / Q52PJ5 / dihydropyrimidinase-like 3 / Q14195*  / complex
 ENSDARG00000045087 cdk5r1b / cyclin-dependent kinase 5, regulatory subunit 1b (p35) / Q15078* / P61809* / CDK5R1* / cyclin dependent kinase 5 regulatory subunit 1* / Cyclin-dependent kinase 5 activator 1 Cycl...  / reaction / complex
 ENSDARG00000056683 cdk5 / cyclin-dependent kinase 5 / P49615* / Q00535* / Cyclin-dependent-like kinase 5 *  / reaction / complex
 ENSDARG00000052468 si:dkeyp-80c12.7 / GSK3B (1 of many) / GSK3B* / P49841* / Q9WV60* / glycogen synthase kinase 3 beta*  / reaction
 ENSDARG00000037916 cdk5r1a / cyclin-dependent kinase 5, regulatory subunit 1a (p35) / Q15078* / P61809* / CDK5R1* / cyclin dependent kinase 5 regulatory subunit 1* / Cyclin-dependent kinase 5 activator 1 Cycl...  / reaction / complex
 ENSDARG00000011370 fyna / Q6EWH2 / FYN proto-oncogene, Src family tyrosine kinase a / FYN* / P06241* / P39688* / Tyrosine-protein kinase Fyn * / FYN proto-oncogene, Src family tyrosine kinase*  / reaction / complex
 ENSDARG00000102153 nrp1a / neuropilin 1a / NRP1* / O14786* / P97333* / neuropilin 1*  / reaction / complex
 ENSDARG00000103490 dpysl4 / dihydropyrimidinase-like 4 / O14531*  / complex
 ENSDARG00000011449 fes / FES proto-oncogene, tyrosine kinase / P07332* / P16879* / Tyrosine-protein kinase Fes/Fps *  / reaction / complex






 

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