ENSG00000004059


Homo sapiens

Features
Gene ID: ENSG00000004059
  
Biological name :ARF5
  
Synonyms : ADP ribosylation factor 5 / ARF5 / P84085
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q32.1
Gene start: 127588345
Gene end: 127591705
  
Corresponding Affymetrix probe sets: 201526_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000000233
Ensembl peptide - ENSP00000412701
NCBI entrez gene - 381     See in Manteia.
OMIM - 103188
RefSeq - NM_001662
RefSeq Peptide - NP_001653
swissprot - C9J1Z8
swissprot - A4D0Z3
swissprot - P84085
Ensembl - ENSG00000004059
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arf4aENSDARG00000103858Danio rerio
 arf4aENSDARG00000045989Danio rerio
 arf5ENSDARG00000070472Danio rerio
 zgc:77650ENSDARG00000113899Danio rerio
 ARF5ENSGALG00000043476Gallus gallus
 Arf5ENSMUSG00000020440Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ARF4 / P18085 / ADP ribosylation factor 4ENSG0000016837489
ARF1 / P84077 / ADP ribosylation factor 1ENSG0000014376181
ARF3 / P61204 / ADP ribosylation factor 3ENSG0000013428779
AC073610.3ENSG0000027282264
ARF6 / P62330 / ADP ribosylation factor 6ENSG0000016552763
P36406 / TRIM23 / tripartite motif containing 23ENSG0000011359556
ARL2 / P36404 / ADP ribosylation factor like GTPase 2ENSG0000021346547
ARL14 / Q8N4G2 / ADP ribosylation factor like GTPase 14ENSG0000017967444
ARL3 / P36405 / ADP ribosylation factor like GTPase 3ENSG0000013817542
ARL11 / Q969Q4 / ADP ribosylation factor like GTPase 11ENSG0000015221339
ARL2-SNX15 / ARL2-SNX15 readthrough (NMD candidate)ENSG0000027300332
ARL15 / Q9NXU5 / ADP ribosylation factor like GTPase 15ENSG0000018530532
ARL8B / Q9NVJ2 / ADP ribosylation factor like GTPase 8BENSG0000013410831
ARL8A / Q96BM9 / ADP ribosylation factor like GTPase 8AENSG0000014386229


Protein motifs (from Interpro)
Interpro ID Name
 IPR005225  Small GTP-binding protein domain
 IPR006689  Small GTPase superfamily, ARF/SAR type
 IPR024156  Small GTPase superfamily, ARF type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER IGI
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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