ENSG00000134287


Homo sapiens

Features
Gene ID: ENSG00000134287
  
Biological name :ARF3
  
Synonyms : ADP ribosylation factor 3 / ARF3 / P61204
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q13.12
Gene start: 48935723
Gene end: 48957551
  
Corresponding Affymetrix probe sets: 200011_s_at (Human Genome U133 Plus 2.0 Array)   200734_s_at (Human Genome U133 Plus 2.0 Array)   211622_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000256682
Ensembl peptide - ENSP00000438063
Ensembl peptide - ENSP00000446353
Ensembl peptide - ENSP00000438510
Ensembl peptide - ENSP00000395370
Ensembl peptide - ENSP00000437374
NCBI entrez gene - 377     See in Manteia.
OMIM - 103190
RefSeq - XM_006719391
RefSeq - NM_001659
RefSeq - XM_005268856
RefSeq Peptide - NP_001650
swissprot - F5H6T5
swissprot - A0A024R0Y6
swissprot - P61204
swissprot - F5H0C7
swissprot - F5H1V1
Ensembl - ENSG00000134287
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arf3aENSDARG00000070539Danio rerio
 Arf3ENSMUSG00000051853Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ARF1 / P84077 / ADP ribosylation factor 1ENSG0000014376196
ARF5 / P84085 / ADP ribosylation factor 5ENSG0000000405978
ARF4 / P18085 / ADP ribosylation factor 4ENSG0000016837477
AC073610.3ENSG0000027282275
ARF6 / P62330 / ADP ribosylation factor 6ENSG0000016552766
P36406 / TRIM23 / tripartite motif containing 23ENSG0000011359559
ARL2 / P36404 / ADP ribosylation factor like GTPase 2ENSG0000021346546
ARL14 / Q8N4G2 / ADP ribosylation factor like GTPase 14ENSG0000017967445
ARL3 / P36405 / ADP ribosylation factor like GTPase 3ENSG0000013817545
ARL11 / Q969Q4 / ADP ribosylation factor like GTPase 11ENSG0000015221339
ARL8B / Q9NVJ2 / ADP ribosylation factor like GTPase 8BENSG0000013410833
ARL15 / Q9NXU5 / ADP ribosylation factor like GTPase 15ENSG0000018530532
ARL8A / Q96BM9 / ADP ribosylation factor like GTPase 8AENSG0000014386232
ARL2-SNX15 / ARL2-SNX15 readthrough (NMD candidate)ENSG0000027300331


Protein motifs (from Interpro)
Interpro ID Name
 IPR005225  Small GTP-binding protein domain
 IPR006689  Small GTPase superfamily, ARF/SAR type
 IPR024156  Small GTPase superfamily, ARF type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006661 phosphatidylinositol biosynthetic process TAS
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER IGI
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity TAS
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the Golgi membrane
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000143393 PI4KB / Q9UBF8 / phosphatidylinositol 4-kinase beta  / complex / reaction






 

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