ENSG00000113595


Homo sapiens

Features
Gene ID: ENSG00000113595
  
Biological name :TRIM23
  
Synonyms : P36406 / TRIM23 / tripartite motif containing 23
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q12.3
Gene start: 65589680
Gene end: 65625975
  
Corresponding Affymetrix probe sets: 204732_s_at (Human Genome U133 Plus 2.0 Array)   210994_x_at (Human Genome U133 Plus 2.0 Array)   210995_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000274327
Ensembl peptide - ENSP00000427103
Ensembl peptide - ENSP00000424044
Ensembl peptide - ENSP00000422144
Ensembl peptide - ENSP00000370406
Ensembl peptide - ENSP00000231524
NCBI entrez gene - 373     See in Manteia.
OMIM - 601747
RefSeq - XM_017009444
RefSeq - NM_001656
RefSeq - NM_033227
RefSeq - NM_033228
RefSeq - XM_005248497
RefSeq Peptide - NP_150230
RefSeq Peptide - NP_150231
RefSeq Peptide - NP_001647
swissprot - P36406
swissprot - D6R9E9
swissprot - D6RD22
swissprot - D6RBN4
Ensembl - ENSG00000113595
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trim23ENSDARG00000069420Danio rerio
 TRIM23ENSGALG00000014765Gallus gallus
 Q8BGX0ENSMUSG00000021712Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ARF3 / P61204 / ADP ribosylation factor 3ENSG0000013428719
ARF1 / P84077 / ADP ribosylation factor 1ENSG0000014376119
ARF5 / P84085 / ADP ribosylation factor 5ENSG0000000405918
ARF4 / P18085 / ADP ribosylation factor 4ENSG0000016837418
ARF6 / P62330 / ADP ribosylation factor 6ENSG0000016552716
AC073610.3ENSG0000027282215
ARL2 / P36404 / ADP ribosylation factor like GTPase 2ENSG0000021346514
ARL14 / Q8N4G2 / ADP ribosylation factor like GTPase 14ENSG0000017967413
ARL3 / P36405 / ADP ribosylation factor like GTPase 3ENSG0000013817513
ARL11 / Q969Q4 / ADP ribosylation factor like GTPase 11ENSG0000015221312
ARL15 / Q9NXU5 / ADP ribosylation factor like GTPase 15ENSG0000018530510
ARL8B / Q9NVJ2 / ADP ribosylation factor like GTPase 8BENSG000001341089
ARL8A / Q96BM9 / ADP ribosylation factor like GTPase 8AENSG000001438629
ARL2-SNX15 / ARL2-SNX15 readthrough (NMD candidate)ENSG000002730038


Protein motifs (from Interpro)
Interpro ID Name
 IPR000315  B-box-type zinc finger
 IPR001841  Zinc finger, RING-type
 IPR003649  B-box, C-terminal
 IPR005225  Small GTP-binding protein domain
 IPR006689  Small GTPase superfamily, ARF/SAR type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR024156  Small GTPase superfamily, ARF type
 IPR027370  RING-type zinc-finger, LisH dimerisation motif
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016567 protein ubiquitination IDA
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 biological_processGO:0045087 innate immune response IEA
 cellular_componentGO:0000139 Golgi membrane IDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003924 GTPase activity IDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IDA
 molecular_functionGO:0008047 enzyme activator activity TAS
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019003 GDP binding IDA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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